Evalution of the exposure to pollutants in the drinking water of So-ava municipality using biomarkers: epidemiological study

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Research Paper 01/02/2014
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Evalution of the exposure to pollutants in the drinking water of So-ava municipality using biomarkers: epidemiological study

Kinsiclounon Gilles E., Koumolou Luc., Guedenon Patient, Agossadou Angélique, Tevi Mirelle, Deguenon Yvette, Kaki Christophe, Loko Frederic, Boko Michel, Gbeassor Messanvi, Edorh Patrick A
J. Bio. Env. Sci.4( 2), 378-392, February 2014.
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Abstract

The previous works revealed the existence of the risks of exposure to pollutants through the consumption of the water in the localities of Ahomey and Houédo in Sô-Ava. It was thus advisable to look for biomarkers, indicators of exposure to these toxics. In this context, a survey was conducted at first to identify the characteristic disorders connected to exposure to xenobiotics. This survey was completed by biochemical and hematological analyses of blood and urine of the investigated. The results revealed that: the characteristic clinical signs to lead and/or cadmium poisoning existed within the population; in particular, stomach pain, , symptoms connected to the reproduction, sign of bone pain, mental retardation, , asthenia, arterial high blood pressure, sight impairment, excessive perspiration, neurological and renal signs. Also in exposure areas, correlation between blood lead and lead in drinking water was high but that correlation was weak for cadmium. Besides, 80 % of the investigated presented a concealed anemia. Other hematological and biochemical values were within the standards, and there was no major disturbance at this level. In respect of urine analyses, there was blood in the urine of 45.16 %, leukocytes of 38.71 %, proteins of 41.94 % and nitrites of 80 % of the exposed population. No glucose was found in the urine but the excretion of calcium is sometimes very alarming with certain individuals especially in the localities where the exposure is high.

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