Exploration of biofilm formation and its association with the clinical and molecular characteristics of Staphylococcus aureus

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Research Paper 01/03/2017
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Exploration of biofilm formation and its association with the clinical and molecular characteristics of Staphylococcus aureus

Qamar Majeed, Ahsan Naveed
Int. J. Biosci.10( 3), 374-381, March 2017.
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Bio film is the complex community of different microorganisms that associated or attached to the surfaces. These microbial communities are composed of multiple species in which different organisms interact with each other and with the environment. In these organisms, Staphylococcus aureus are the most important which have a vital role in bio film formation. By developing this complex community, Staphylococcus aureus become more resistant towards antimicrobial agents. Methiciline resistant Staphylococcus aurues have resistant against methicilline by developing the complex community with many other organisms. New methodologies and experimental work have been done to explore the phylogenetic grouping, metabolic interaction, and competition among other members of the bio film. For the mere advancement, we reviewed here the bio film ecology, model organisms which have been investigated using different molecular techniques and identify the gene required for the development of bio film. Recently, bio film formation has led to amazing progress for studying advanced ecological significance of bacteria and provide the new approaches in the molecular genetics of bio film formation.


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