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Frequency of common hematological manifestations determined in newly diagnosed HIV infected patients

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Research Paper 01/09/2017
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Frequency of common hematological manifestations determined in newly diagnosed HIV infected patients

Yaseen Khan, Humaira Chauhan, Hashmat Ullah, Eiman Sumayyah, Sahib Zada, Wasim Sajjad
Int. J. Biosci.11( 3), 31-40, September 2017.
Certificate: IJB 2017 [Generate Certificate]
Key: Common hematological manifestationsHIV infectedNewly diagnosed

Abstract

Globally the phenomenon of Human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) is noticed as pandemic, which affects almost all countries around the globe. Presently in Asia, about 4.9 million population are infected with HIV. It attacks the immune system of human body. Generally, the immune system generates several infection counter cells called T-cell lymphocytes. After infecting the immune system, within months to years, all the T-cell lymphocytes get destroy. Current study was aimed to determine the frequency of common hematological manifestations in newly diagnosed HIV infected patients. In this study, total of 271 patients were observed by using prevalence of neutropenia 2.29%, 95% confidence interval and 2% margin error using WHO sample size calculator. Moreover, non-probability consecutive sampling was used to collect samples. In this study, the mean age was 32 ± 3.51 years. 62%percent patients were male and 38% patients were female. Hematological manifestations were analyzed as 80% patients had anemia, 38% patients had total leucocyte count < 4000/µL, 20% patients had absolute lymphocyte count < 800/µL, 5% patients had absolute neutrophil count < 1000 /µL while 15% patients had total platelet count <150,000. Our study concludes that the most common hematological manifestations was anemia 80% followed by total leucocyte count < 4000/µL (38%), absolute lymphocyte count < 800/µL (20%), total platelet count <150,000 (15%) and absolute neutrophil count < 1000 /µL (5%).

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