Health perspectives of licorice (Glycyrrhiza glabra Linne.)
Paper Details
Health perspectives of licorice (Glycyrrhiza glabra Linne.)
Abstract
Licorice (Malthi) has been used for thousands of years worldwide as a medicinal remedy with several pharmacologic properties in antique medicine and as a sweetening agent in food products. It has various health advantages and is used to combat various diseases and symptoms. The main objective of this study is to demonstrate the therapeutic effects and health perspectives of licorice (Glycyrrhiza glabra) for safety. It is a significant source of phytochemicals such as flavonoids, iso-flavonoids, triterpene, saponins and glabridin that exhibits a wide range of biological activities, including hepatoprotective, anticular, anti-inflammatory, antiviral, and anticancer activity. Combined use with licorice derivatives and prescription chemotherapy drugs significantly increases the efficacy of anticancer and decreases the side effects of chemotherapy. In addition, glycirizic acid and glycyrrhetinic acid in licorice have been indicated in drug delivery systems targeted for hepatocellular carcinoma treatment to present liver targeting effects. The licorice extracts controls the inflammation and neurotoxicity that leads to Parkinson’s disease. The results indicates that ethanolic extract of licorice is more active in treatment of diabetes, insulin resistance, reducing obesity and ameliorating hypertension, dyslipidemia and suggest that licorice ethanolic extract are effective in preventing and ameliorating the metabolic syndrome. This review aims to outline the current health outlook and medicinal properties and pathways of extract and gain new perspectives for further research and development in licorice.
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Sana Noreen, Bahisht Rizwan, Aiman Ijaz, Muhammad Imran, Sameen Azhar, Tehreem Nisar (2020), Health perspectives of licorice (Glycyrrhiza glabra Linne.); IJB, V16, N3, March, P558-565
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