In vitro biological screening of crude extract and different fractions of Mirabilis jalapa

Paper Details

Research Paper 01/08/2019
Views (955)
current_issue_feature_image
publication_file

In vitro biological screening of crude extract and different fractions of Mirabilis jalapa

Shafaat Ullah, Bashir Ahmad, Zaid Ullah, Muhammad Idrees, Amjad Hussain, Yaqoob ur Rehman, Farhana Jabeen shah
Int. J. Biosci. 15(2), 595-599, August 2019.
Copyright Statement: Copyright 2019; The Author(s).
License: CC BY-NC 4.0

Abstract

The objectives of the current project were to analyze the phytotoxic, insecticidal and anti-termites activities of MJME (Mirabilis jalapa Methanolic Extract) and it successive solvent fractions. Methanol preparation and its different fractions were utilized to assess the phytotoxic, insecticidal and anti-termites activities of the selected plant. The MJME and its various fractions expressed low to good potentials against the Lemna minor at various concentrations. These fractions were also investigated for their insecticidal potentials, eliciting good activity against the tested insects. The crud extract and its various fractions were also tested for their anti-termites activity expressed good results. Phytotoxic, insecticidal and anti-termites activities of MJME and its various fractions were significant. Extensive researches are need of the hour to collect pure constituents practiced in the synthesis of novel and effective medications.

Ahmad B, Azam S, Bashir S, Hussain F, Chaudhary MI. 2011. Insecticidal, brine shrimp cytotoxicity, antifungal and nitric oxide free radical scavenging activities of the aerial parts of Myrsine africana L. African Journal of Biotechnology 10, 1448-1453. DOI: 10.5897/AJB10.1652 

Bakht J, Ali H, Khan MA, Khan A, Saeed M, Shafi M, Islam A, Tayyab M. 2011. Antimicrobial activities of different solvents extracted samples of Linum usitatissimum by disc diffusion method. African Journal of Biotechnology 10, 19825-19835. doi.org/10.5897/AJB11.229

Chetty KM, Sivaji K, Rao KT. 2008. Students offset printers, Tirupati. 256.

Idrees M, Ahmad B, Ahmad K, Bashir S, Ali A, Aman K. 2018. Anti-tuberculous, phytotoxic and insecticidal activities of secondary metabolites obtained from aspergillus and penicillium species isolated from soil. Journal of Pakistan Medical Association 68, 1024-28.

Khan T, Ahmed M, Khan R, Khan H, Choudhary MI. 2008. Phytotoxic and insecticidal activities of medicinal plants of Pakistan, Trichodesma indicum, Aconitum laeve and Sauromatum guttatum. Journal of the Chemical Society of Pakistan 30, 251-255.

Khattak SG, Gilani SN, Ikram M. 1985. Antipyretic studies on some indigenous Pakistani medicinal plants. Journal of ethnopharmacology 4, 45-51. doi.org/10.1016/0378-8741(85)90027-3

McLaughlin JL, Chang CJ, Smith DJ. 1991. Bench-Top bioassays for the discovery of bioactive natural products an update. In: Atta-ur-Rahman (ed.) Studies in Natural Products Chemistry. Amsterdam:Elsevier Sci. Publishers.

Mishra BB, Tiwari VK. 2011. Natural products: An evolving role in future drug discovery. European Journal of Medicinal Chemistry 46, 4769-807. doi.org/10.1016/j.ejmech.2011.07.057

Newman DJ, Cragg GM, Snader KM. 2000. Natural product reports 17, 215-234. 10.1039/ A902202C

Rehman AU. 1991. Studies in Natural Product Chemistry. Elsevier Science Publishers, Netherlands 9, 383-409.

Salihah Z, Khatoon R, Khan A, Alamzeb SA. 1993. Conference. Paper presented at the Proceeding Pakistan Cong Zool 395-400.

Sheikh TB, Hatcher J. 2005. Evidence-Based Complementary and Alternative Medicine 2, 139-142.

Related Articles

In vitro assessment of the anticancer activity of quinaldic acid against human breast cancer cells (MCF-7)

N. Medhavi, S. M. Sivasankaran, K. Selvakumar, K. Harish, S. Manoharan*, Int. J. Biosci. 29(3), 1-10, September 2026.

In silico molecular docking analysis of quinaldic acid against cancer related targets

N. Medhavi, K. Harish, S. M. Sivasankaran, K. Selvakumar, B. Vidhyambigai, S. Manoharan*, Int. J. Biosci. 29(2), 129-139, August 2026.

First records of Macrogyrodactylus clarii and six species of Quadriacanthus (Monogenea) infecting Clarias gariepinus (Burchell, 1822) across four localities in Senegal

Arfang Diamanka*, Abdou Toure, Sikhou Drame, Cheikh Diop, Ngor Faye, Int. J. Biosci. 29(2), 118-128, August 2026.

Comparative predictive performance of anthropometric indices and associated risk factors for obesity among Beninese adults: A cross-sectional study

Ganlaky D. Boris, Sègbo Julien A. Gaetan*, Dossou David, Sossa J. Charles, Akpovi D. Casimir, Agbangla Clement, Int. J. Biosci. 29(2), 105-117, August 2026.

Proximate, mineral and vitamin composition of Uvaria chamae P. Beauv. (Annonaceae) seed flour from Korhogo, northern Côte d’Ivoire

Nyamien Yves Bleouh Jean*, Anon Attoh Hyacinthe, Diallo Koffi, Biego Godi Henri, Int. J. Biosci. 29(2), 97-104, August 2026.

Acute toxicity of seeds from Sphenostylis stenocarpa (Hochst ex A. Rich.) Harms

Wilfried Zanmenou*, Razack Osseni, Mahouglo Barnabé Houessou, Chimène Agrippine Rodogune Yelouassi, Comlan Kintomagnimessè Célestin Tchekessi, Philippe Sessou, Anatole Laleye, Pierre Dossou-Yovo, Int. J. Biosci. 29(2), 89-96, August 2026.

Stabilization of cashew apple juice with chitosan: clarification and microbiological quality

Kokora Aya Philomène*, Coulibaly Adama, Cissé Mohamed, Coulibaly Bintou, Konan N’guessan Ysidor, Godi Henri Marius Biego, Int. J. Biosci. 29(2), 76-88, August 2026.

Implementation and evaluation of limited face to face classes: basis for adoption of health and safety manual

Christian Jude B. Calunsag*, Int. J. Biosci. 29(2), 65-75, August 2026.