In vitro inhibition potential of Forsskaolea tenacissima L. against four pathogenic bacterial strains

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Research Paper 01/08/2018
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In vitro inhibition potential of Forsskaolea tenacissima L. against four pathogenic bacterial strains

Abd Ullah, Rohul Amin, Adnan Khan
J. Bio. Env. Sci.13( 2), 200-208, August 2018.
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In recent past the use of plant or plant parts as potential antimicrobial agent became an attractive approach due to alarmingly increase in antibiotic resistance. The present study was aimed to evaluate the antibacterial potential of three different crude extracts (chloroform, aqueous and ethyl acetate) of Forsskaolea tenacissima L. against four pathogenic bacterial strains at four different concentrations (0.5, 1.0, 1.5, the 2.0 mg/ml) using agar well diffusion assay. Ethyl acetate root extracts exhibited wondrous inhibition against Staphylococcus aureus and Klebsiella pneumonia with inhibition zone recorded as 26.67 and 25.44mm at 2.0mg/ml respectively. Chloroform root extract at 2.0mg/ml concentration also showed tremendous effect with an inhibition zone of 25.34 mm. Bacterial strains were most sensitive to root crude extracts followed by stem and leaves crude extracts. Bacillus subtilis and Pseudomonas aeruginosa were least sensitive to leaves aqueous crude extracts with an inhibition zone of 5.44mm and 6.64mm at 2.00mg/ml respectively. The inhibition potential was concentration dependent. The inhibition was maximum at high concentration and showing a decrease with the decrease in concentration from 2mg/ml to 0.5mg/ml. The present findings support the use of F. tenacissima L. as a tool in the management of pathogenic bacterial strains.


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