Investigation for phytochemical composition, antioxidant activities and antibacterial properties of Achyranthes aspera L.
Paper Details
Investigation for phytochemical composition, antioxidant activities and antibacterial properties of Achyranthes aspera L.
Abstract
Plants and plant-based medicines form the foundation of many modern pharmaceuticals used to treat various ailments. Thus, this study aimed to investigate the phytochemical, antioxidant, and antibacterial properties of A. aspera leaves. Phytochemical screening revealed the presence of alkaloids, flavonoids, terpenoids, glycosides, carbohydrates, coumarins, and steroids in both ethanol and methanol extracts. However, cardiac glycosides and phenols were exclusively found in the ethanol extract. Methanol leaf extracts exhibited the highest levels of flavonoids (41.16 mg QE/gm) and phenols (9.99 mg GAE/gm), respectively. Significant antioxidant activity was observed with IC50 values of 237.83 μg/ml and 279.14 μg/ml for methanol and ethanol leaf extracts, respectively. The antibacterial efficacy of A. aspera leaf extracts was tested against Bacillus sp., E. coli, and Enterobacter sp. Methanolic extracts showed stronger antibacterial effects compared to ethanolic extracts, with the highest zone of inhibition (20.67 mm) against Bacillus sp. and the lowest MIC (75 mg/ml) and MBC (150 mg/ml) values. These findings suggest that A. aspera leaf extract could serve as a source of novel antioxidant and antibacterial compounds.
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