L-asparaginase gene – a therapeutic approach towards drugs for cancer cell
Paper Details
L-asparaginase gene – a therapeutic approach towards drugs for cancer cell
Abstract
L-asparaginase is an enzyme that reduces the activity of L-asparaginase (an important nutrient for cancer cells) resulting in cancer/tumor cell starvation). L-asparaginase is relatively wide spread enzyme found in many plant tissue, bacteria, plant and in the serum of certain rodents, but not of man. It is used mainly for the induction of remission in acute lymphoblastic leukemia. Although there are therapeutic asparaginases present in the market, recent discoveries have indicated that the L-asparaginase from Erwinia carotovora (ErCAR) might be more efficient and also to exhibit fewer side effects. The need for new therapeutic enzymes is of great interest in both biotechnology and medicine. This paper is an attempt to comprise detailed information of the work on the L-asparaginase gene from different sources for the treatment of cancer cells.
Albanase E & Kafkewitz D. 1978. Effect of media composition on the growth and asparaginase production of vibrio succinogenes. Applied Environmental Microbiology 36, 25-30.
Ali SS. 1994. A fungal L-asparaginase with potential antitumor activity. Indian Journal of Microbiology 34, 73-76.
Barnes WR, Dorn GL, Vela GR. 1977. Effect of culture conditions on synthesis of L asparaginase by Escherichia coli A-1. Appl Environ Microbiol. 33(2), 257–261.
Bell TL, Adams MA. 2004. Ecophysiology of ectomycorrhizal fungi associated with Pinus spp, Plant Ecology 171(1-2), 35-52.
Benny PJ, Kurup GM. 1991. L-asparaginase activity in bacteria from estuarine sediments and mollusks. Indian Journal of Marine Sci. 20, 36-39.
Berenbaum MC, Ginsburg H, Gilbert DM. 1970. Effects of L-asparaginase on lymphocyte target cell reactions. In Vitro Nature 227, 1147–1148.
Bon EP. 1997. Asparaginase II of Saccharomyces cerevisiae. GLN3/URE2 reulation of a periplasmic enzyme. Appl Biochem Biotechnol. 63/65. 203-212
Bonthron DT. 1990. L-asparaginase of Escherichia coli by N-bromo succinimide. Khimiya prirodnykh Soedinenil (2), 228-231.
Borisov AA, Eldarow MA, Zgoon AA, Alexandrova SA, Omelyn NN, Sokov BN, Berezov TT, Sokolov NN. 2003. Purification and some properties of recombinant Erwinia carotovora L-asparaginase, expressed in Escherichia coli homolog. Eur J Biochem. 271(15), 3215-3226.
Borek D, Podkowinski J, Kisiel A, Jasloski. M. 1999. Isolation and characterization of c-DNA encoding L-asparaginase from Luponus lutetus (Accession No, AF 112444), Plant Physiol. 119, 1568-1570.
Borek D, Jasloski. M. 2000. Crystalization and preliminary crystallographic studies of a new L-asparaginase encoded by Escherichia coli genome, Acta crystallographica Section D Biological Crystallograph 56(11), 1505-1507.
Borkotaky B, Bezbaruah RL. 2002. Production and Properties of of asparaginase from a new Erwinia sp. Folia Microbiologica 47(5), 473-476.
Broome JD. 1963. L-asparaginase EC-II from Escherichia coli. Some substrate specificity characteristics. Biochemistry 8, 3766-3772
Campbell HA. 1967. Two Asparaginase from Escherichia coli B, their separation, purification and antitumor property. Biochemistry 6, 721-730
Ciustea M, Guitierrez JA, Abbatiello SE, Evler, JR, Richards NG. 2005. Efficient expression, purification and characterization of C-terminal tagged, recombinant human asparaginase synthtase. Arch Biochem Biophys 440(1), 18-27
Dhevendaran K, Anithakumari YK. 2002. L-asparaginase activity in growing conditions of Streptomyces spp. Associated with Therapon jarbua and Villorita cyprinoids Veli Lake, South India. Fishery Technology 39(2), 155-159
Dickson JMJJ, Vincze E, Grant MR, Smith LAA, Redber KA, Fardnden KJF, Reynolds PHS. 1992. Molecular Cloning of the gene encoding developing seed L-asparaginase from Lupinus angustifolius. Plant Molecular Biology 20(2), 333-336.
Drainas D, Drainas C. 1985. A conductimetric method for assaying asparaginase with antilymphoma activity from Vibrio succinogenes. J. Biol Chem. 251, 6929-6933.
Dunlop PC, Meyer GM, Ban D, Roon RJ. 1978. Characterization of two forms of asparaginase in Scccharomyces crevisiae. Journal of Biological Chemistry 253(4), 1297-1304.
Eliba PS. 1997. Bon, Elvira carvajal, Mike stanbrough, Donald rowen and Boris magasanik Asparaginase II of Saccharomyces cerevisiae GLN3/URE2 regulation of a periplasmic enzyme Applied Biochemistry and biotechnology 63-65.
Foda MS, Zedan HH, Hashem SAEM. 1980. Characterization of novel L-asparaginase produced by Rhodotula rubra. Revista Latinoamericana de Microbiologia 22(2), 87-96.
Garaev MM, Golub EI. 1977. Mechanism of the effect of the glucose on L-asparaginase synthesis by Escherichia coli bacteria. Mikrobiologiiya 46(3), 433-439.
Gunasekran S, McDonald L, Manavathu M, Manavathu E, Gunasekran M. 1995. Effect of culture media on growth and L-asparaginase production in Nocardia asteroids. Biomedical Letters 52(207), 197-201.
Harry JG. 1986. Cloning and expression for Erwinia crysanthmi asparaginase gene in Escherichia coli and Erwinia carotovora. J. Gen Micrrobiol. 132, 151-160
Head DR, Behm FG. 1995. Acute lymphoblastic leukemia and the lymphoblastic lymphomas of childhood. Semin Diagn Pathol. 12(4), 325-34.
Irino T, Kitoh T, Koami K, Kashima T, Mukai K, Takeuchi E, Hongo T, Nakaheta T, Schuster SM, Osaka M. 2004. Establishment of real time PCR method for quantitative analysis of L-asparagines synthetase expression, J Mol Diagn. 6(3), 217-224
Jennings MP, Beacham IR. 1993. Co-dependent positive regulation of the ans B promoter of Escherichia coli by CRP and the FNR protein: A molecular analysis. Molecular Microbiology 9(1), 155-164.
Kafkewitz D, Goodman D. 1974. L-asparaginase production by the rumen anaerobe Vibrio succinogenes. Appl Microbiol. 27, 206-209.
Khushoo A, Pal Y, Singh BN, Mukherjee KJ. 2004. Expression and single step purification of recombinant Escherichia coli L-asparaginase-II. Protein Expression and Purification 38(1), 29-36.
Khushoo A, Pal Y, Mukherjee KJ. 2005. Optimization of extracellular production of recombinant asparaginase in Escherichia coli in shake flask and bioreactor. Appl Microbiol Biotechnol. 68(2), 189-197.
Kil JG. 1953. Regeneration of transplanted lymphomas induced in vivo by means of normal Guinea pig serume. J Exp Med. 98, 583-591.
Kotzia GA, Labrou NE. 2006. L-asparaginase from Erwinia chrysanthemi 3937: Cloning , expression and characterization. Biotechnol. 127(4), 657-669.
Krastkna J, Borisova AA, Gervaziev YV, sokolav NN. 2004. One step purification and kinetic properties of the recombinant L-asparaginase from Erwinia carotovora. Biotechnol Appl Biochem. 39(2), 215-221.
Lough TJ, Chang KS, Carne A, Monk BC, Reynolds PHS, Farnden KJF. 1992. L-asparaginase from developing seed of Lupinus arboreus. Phytochemistry 31(5), 1519-1527.
Mahopatra BR. 1997. Production and properties of L-asparaginase from Mucor sp. associated with a marine sponge (spirastrlla sp.). Cytobios 92, 165-173.
Mardashev SR, Nikoaev AY, Sokolov NN, Kozlov EA, Kutsman ME. 1975. Isolation and properties of homogenous L-asparaginase preparation from Pseudomona flourescens AG. Bokhimiya 40(5), 984-989.
Martins JF. 1989. Molecular genetics of amino acid producing Corynebacteria. Symp Soc Gen Microbiol. 72, 671-680.
Mesas JM. 1990. Characterization and partial purification of L-asparaginase from Corynebacterium glutamicum. J Gen Microbiol. 136, 515-519.
Michel V. 2003. The enzyme as a drug: application of enzyme as pharmaceuticals. Current opinion in Biotechnology 14, 444-450.
Mikucki J. 1997. Factors influencing L-asparaginase production by Staphylococci. Zentrallbl Bakteriol Parasentenkd Infektionskr Hyg 132, 135-142.
Moola ZB. 1994. Erwinia chryseanthemi L-asparaginase: epotope mapping and production of antigenically modified enzyme. Biochem J. 302, 921-927.
Mostafa SA. 1979. Activity of L-asparaginase in cells of Streptomyces karnatakensis. Zentralbl Bacteriol (Naturwiss) 134, 343-351.
Mostafa SA, Salama MS. 1979. L-asparagine producing Streptomyces from soil of Kuwait. Zentralbl Bakterio (Naturwiss) 134, 325-334.
Mukherjee J. 2000. Studies on nutritional and oxygen requirements for production of L-asparaginase by Enterobacter aerogenes. Appl Microbiol Biotechnol. 53, 180-184.
Nachman JB, Sather HN, Sensel MG. 1998. Augmented post-induction therapy for children with high-risk acute lymphoblastic leukemia and a slow response to initial therapy. N Engl J Med. 338, 1663-1671.
Netrval J. 1977. Stimulation of L-asparaginase production in Escherichia coli by organic and amino acids. Folia Microbiol (Praha) 22, 106-116.
Paul JH. 1982. Isolation and characterization of a Chlamydomonas Lasparaginase. Biochemical J 203, 109-115.
Pritsa AA, Kyriakidis DA. 2001. L-asparaginase of Thermus thermophilus: Purification, properties and identification of essential amino acids for its catalytic activity. Mil cell Biochem. 216, 93-101
Raha SK. 1990. Purification and properties of L-asparaginase from Cyllindrocarpron obtusisporum MB-10. J Biochem Int. 21, 987-1000.
Rozalska M, Mikucki J. 1992. Staphylococcal L-asparaginase: Catabolic repression of synthesis. Acta Microbiol Pol. 41, 145-150.
Sanson E, Jaskolsko M. 2004. Structure, Dynamics and Electrostatics of the L-asparaginase catalytic Centre: Implication of reaction mechanism. Department of crystallography, Birkbeck College, London and Venus International ltd. London.
Savitri NA, Wamik A. 2003. Microbial L-asparaginase: A Potent Antitumor Enzyme. Indian Journal of Biotechnology 2, 184-194.
Spring KJ, Jerlstrom PG, Burus DM, Beacham, IR. 1986. L—asparaginase genes in Escherichia coli: Isolation of mutants and characterization of the ANS-A gene and its protein product. Journal of Bacteriology 166(1), 135-142.
Tiwari N, Dua RD. 1996. Purification and preliminary characterization of L-asparaginase from Erwinia aroideae. Indian J Biochem Biophys. 33, 371-376.
Triantafillou DJ, Georgatsos JG, kyriankidis DA 1988. Purification and properties of membrane-bound L-asparaginase of Tetrahymena pyriformis. Molecular and Cellular Biochemistry 81(1), 43-51.
Tsirka S A & Kiriakidis D A 1990. L-asparaginase of Tetrahymena pyriformis is associated with a kinase activity. Mol Cell Biochem 95, 77-78.
Vernour RY. 1994. Adult amino acid requirements: The case for a major revision in current recommendations. The journal of nutrition 124, 1517S-1523S.
Wang B, Relling MV, Storm MC, Woo MH, Ribeiro R, Puri CH, Hak LJ. 2003. Evaluation of immunologic cross reaction of antiasparaginase antibodies in acute lymphoblastic leukemia (ALL) and lymphoma patients. Leukemia 17(8), 1583-1588.
Wang J, Li J, Bachas LG. 2002. Biosensor for asparagine using a thermostable recombinant asparaginase from Archeoglobus fulgidus. Anal Chem. 74(14), 3336-3341.
Nabeel Ahmad, Nitin Prakash Pandit, Sanjiv Kumar Maheshwari (2012), L-asparaginase gene – a therapeutic approach towards drugs for cancer cell; IJB, V2, N4, April, P1-11
https://innspub.net/l-asparaginase-gene-a-therapeutic-approach-towards-drugs-for-cancer-cell/
Copyright © 2012
By Authors and International
Network for Natural Sciences
(INNSPUB) https://innspub.net
This article is published under the terms of the
Creative Commons Attribution License 4.0