Phytochemical screening, anti-diabetic and antioxidant potential of methanolic extract of Indigofera heterantha roots

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Research Paper 01/05/2017
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Phytochemical screening, anti-diabetic and antioxidant potential of methanolic extract of Indigofera heterantha roots

Muhammad Aurang Zeb, Muhammad Sajid, Taj Ur Rahman, Khanzadi Fatima Khattak, Muhammad Tariq Khan
Int. J. Biosci. 10(5), 355-360, May 2017.
Copyright Statement: Copyright 2017; The Author(s).
License: CC BY-NC 4.0

Abstract

The aim of the current study was to detect the Phytochemical present in the methanolic extract of the plant using the biochemical tests and to evaluate the anti-diabetic and antioxidant potential of the methanolic extract of I. heterantha roots using Glucose uptake yeast in cells assay and 1, 1-diphenyl -2-picrylhydrazyl (DPPH) free radical scavenging assay. The methanolic extract showed good anti-diabetic activity with minimum increase 5.31% at 10µg/ml and maximum 53.19% at 80μg/ml glucose concentration while moderate antioxidant activity with minimum radical scavenging activity 22.00% at 200µg/ml and maximum activity 56.35% at 1000µg/ml. The results obtained revealed that this plant is very important from medicinal point of view.

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