Phytochemistry and antioxidant activity of Sclerocarya birrea extracts, A plant used in the traditional management of hypertension in Mali
Paper Details
Phytochemistry and antioxidant activity of Sclerocarya birrea extracts, A plant used in the traditional management of hypertension in Mali
Abstract
Sclerocarya birrea (A. Rich) Hoscht is a popular African wild tree whose leaves, bark, roots and fruits are used in the food and the traditional medicine. The aim of the current study was to determine the phytochemical composition and the antioxidant potential of extracts (aqueous, ethanolic and ethyl acetate macerates) of S. birrea leaves, bark and roots. Thus, a screening based on qualitative techniques was carried out. The total polyphenols were quantified using the Folin-Ciocalteu method, while the flavonoids were quantified using aluminum trichloride. The in vitro antioxidant activity was determined by the DPPH and Phosphomolybdate tests. The phytochemical screening revealed the presence of alkaloids, tannins, flavonoids, coumarins and terpenoids in all extracts. The ethanolic root extracts showed the highest levels of polyphenols (822.6±36.9 mg GAE/g) and flavonoids (112.59±12.29 mg QE/g). As for the antioxidant potential, the ethanolic extracts of bark showed the best DPPH radical reduction capacity, with an IC50 of 65.57±2.32 µg/mL and a total antioxidant capacity of 882.50±25 mg EAA/g. This study showed that S. birrea organs are a potential source of natural antioxidants that could play a crucial role in the management of hypertension.
Abdelwahab SI, Elhassan Taha MM, Mariod AA. 2024. Bibliometric analysis of scientific research on Sclerocarya birrea (A. Rich.) Hochst. Foods and Raw Materials 13(1), 128–143. https://doi.org/10.21603/2308-4057-2025-1-629
Bio A, Toyi S, Yoka J, Djego G, Awede B, Laleye A, Sinsin A. 2015. Contribution aux connaissances des principales plantes antihypertensives utilisées en médecine traditionnelle à Bassila (Bénin, Afrique de l’Ouest). Revue CAMES – Série Pharmacopée et Médecine Traditionnelle 17(2), 8–18. http://publication.lecames.org/index.php/pharm/article/view/653
Bruneton J. 2009. Pharmacognosie, phytochimie, plantes médicinales. 1268.
da Silva RA, Liberio S, do Amaral F, do Nascimento F, Torres L, Neto V, Guerra R. 2016. Antimicrobial and antioxidant activity of Anacardium occidentale L. flowers in comparison to bark and leaves extracts. Journal of Biosciences and Medicines 4(4), 87–99.
Dembélé A, Sissoko L, Togola I, Traoré N, Sidibé L, Diallo D. 2020. Enquête ethnobotanique de trois plantes utilisées dans la prise en charge traditionnelle de l’hypertension artérielle au Mali: Balanites aegyptiaca (L.) Del., Piliostigma reticulatum (DC), Hochst et Bauhinia rufescens (L.). International Journal of Applied Research 6(10), 998–1001. DOI: 10.22271/allresearch.2020.v6.i10o.7683
Drame BS, Kone A, Sylla SD, Goita Y, Coulibaly DM, Sanogo R, Cissé BM. 2022. Capacité antioxydante des feuilles du Moringa oleifera chez les diabétiques de type 2. Health Sciences & Diseases 23(3), 136–144.
Hamata WT, Togola I, Sissoko L. 2020. Caractérisation et évaluation de l’activité anti-radicalaire des feuilles de Moringa oleifera Lam. récoltées dans différentes zones climatiques du Mali. International Journal of Biosciences 17(3), 105–113. https://doi.org/10.12692/ijb/17.3.105-113
Houehanou C, Amidou S, Preux P, Houinato D, Lacroix P. 2018. Hypertension artérielle (HTA) en Afrique subsaharienne. JMV-Journal de Médecine Vasculaire 43(2), 87.
Komane B, Vermaak I, Summers B, Viljoen A. 2015. Safety and efficacy of Sclerocarya birrea (A. Rich.) Hochst (Marula) oil: A clinical perspective. Journal of Ethnopharmacology 176, 327–335.
Konaré MA, Condurache NN, Togola I, Păcularu-Burada B, Diarra N, Stanciuc N, Râpeanu G. 2023. Valorization of bioactive compounds from two underutilized wild fruits by microencapsulation in order to formulate value-added food products. Plants 12(267), 1–19. https://doi.org/10.3390/plants12020267
Konaré MA, Diarra N, Cissé C, Traoré DAK, Togola I, Kassogué A, Sanogo R, Ouattara AS. 2020. Evaluation of the biological activities of leaf and bark extracts of Ficus platiphylla Delile, a medicinal plant used in Mali. Journal of Medicinal Plants Research 14(3), 118–128. https://doi.org/10.5897/JMPR2019.6874
Ngueguim F, Esse E, Dzeufiet P, Gounoue R, Bilanda D, Kamtchouing P, Dimo T. 2015. Oxidised palm oil and sucrose induced hyperglycemia in normal rats: Effects of Sclerocarya birrea stem barks aqueous extract. BMC Complementary Medicine and Therapies 16, 1–11. https://doi.org/10.1186/s12906-016-1009-0
Niang L, Mahamat SA, Ayessou NC, Cisse M, Diop CM. 2021. Antioxidant activity of hydro-Acetonic, hydro-methanolic and aqueous leaf and bark extracts of Sclerocarya birrea (A. Rich.) Hochst. Food and Nutrition Sciences 12, 429–438. https://doi.org/10.4236/fns.2021.125033
Razis A, Ibrahim M, Kntayya S. 2014. Health benefits of Moringa oleifera. Asian Pacific Journal of Cancer Prevention 15(20), 8571–8576.
Samaké A, Diarra L, Keita M, Haidara D, Haidara M, Diallo M, Konaté M, Maiga M, Elméhdi Elansari MAM, Kassogue D, Dao S, Samaké H, Konate K, Dembele B, Coulibaly M, Mariko S, Colette D. 2024. Maternal and perinatal prognosis of arterial hypertension and pregnancy in a peripheral health center in Mali. Open Journal of Obstetrics and Gynecology 14, 855–867. https://doi.org/10.4236/ojog.2024.145069
Sanogo R, Karadji AH, Dembélé O, Diallo D. 2009. Activite diurétique et salidiurétique d’une recette utilisée en médecine traditionnelle pour le traitement de l’hypertension artérielle. Mali Medical Tome XXIV(N°4), 1–6.
Sarode SA, Sonawane YN, Suralkar RK, Kumbhar DD, Warade PP, Patil PR. 2023. Moringa oleifera: Phytochemistry, pharmacology. GSC Biological and Pharmaceutical Sciences 24(03), 041–055. DOI: 10.30574/gscbps.2023.24.3.0352
Sène AL, Niang K, Faye G, Ayessou N, Sagna MB, Cissé M, Diallo A, Cissé O, Gueye M, Guisse A. 2018. Identification des usages de Sclerocarya birrea (A. Rich) Hochst dans la zone du Ferlo (Sénégal) et évaluation du potentiel biochimique et nutritionnel de son fruit. African Journal of Food, Agriculture, Nutrition and Development 18(2), 13470–13487. https://doi.org/10.18697/ajfand.82.17015
Shaikh JR, Patil M. 2020. Qualitative tests for preliminary phytochemical screening: An overview. International Journal of Chemical Studies 8(2), 603–608. DOI: 10.22271/chemi.2020.v8.i2i.8834
Taylor PG, Cesari IM, Arsenak M, Ballen D, Jesús M, Fernández A, Milano B, Ruiz M, Michelangeli F, Taylor PG, Cesari IM, Arsenak M, Ballen D, Abad J, Fernández A, Milano B, Ruiz M, Williams B. 2006. Evaluation of Venezuelan medicinal plant extracts for antitumor and antiprotease activities. Pharmaceutical Biology 44(5), 349–362. DOI: 10.1080/13880200600748119
Togola I, Kaya Y, Diarra N, Konare MA, Denou A, Sanogo R. 2020. Comparative study of the phytochemistry and antioxidant activity of Anacardium occidentale (L.) leaf and stem bark extracts. Journal of Diseases and Medicinal Plants 6(3), 72–76.DOI: 10.11648/j.jdmp.20200603.13
Togola I, Konaré MA, Cissé C, Diarra N. 2023. Anti-inflammatory and anti-cancer activities of leaf extracts from three Datura species found in Mali. Journal of Applied Life Sciences International 26(6), 88–97. DOI: 10.9734/JALSI/2023/v26i6630
Togola I, N’Diaye M, Traoré N, Konaré MA, Diarra N. 2023. Ethnobotanical and comparative study of the antioxidant and anti-inflammatory potential of three organs of Zanthoxylum zanthoxyloides, a plant used in the traditional treatment of sickle-cell disease in Bamako. GSC Biological and Pharmaceutical Sciences 25(01), 19–30. DOI: 10.30574/gscbps.2023.25.1.0402
Traore MS, Camara A, Balde MA, Diallo MST, Barry NS, Balde ES, Balde AM. 2022. Ethnobotanical survey of medicinal plants used to manage hypertension in the Republic of Guinea. Journal of Pharmacy and Pharmacognosy Research 10(5), 938–951. DOI: 10.56499/jppres22.1470_10.5.938
Traoré T, Sidibé K, Traoré B, Sidibé BM, Sanogo A, Sylla C, Beye SA, Kané F, Boiré S, Traoré B, Fomba D, Dougnon S, Traoré Y, Téguété I, Mounkoro, Menta I, Touré M. 2021. Hypertension artérielle et grossesse: Aspects épidémiocliniques et complications à l’Hôpital Nianankoro Fomba de Ségou. Health Sciences & Diseases 22(9), 94–97. www.hsd-fmsb.org
Mamadou A. Konaré, Hadiza Bawa Ibrahim, Fanta Sanogo, Cheickna Cisse, Issiaka Togola, Nouhoum Diarra (2024), Phytochemistry and antioxidant activity of Sclerocarya birrea extracts, A plant used in the traditional management of hypertension in Mali; IJB, V25, N2, August, P75-82
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