Phytochemistry and antioxidant activity of Sclerocarya birrea extracts, A plant used in the traditional management of hypertension in Mali
Paper Details
Phytochemistry and antioxidant activity of Sclerocarya birrea extracts, A plant used in the traditional management of hypertension in Mali
Abstract
Sclerocarya birrea (A. Rich) Hoscht is a popular African wild tree whose leaves, bark, roots and fruits are used in the food and the traditional medicine. The aim of the current study was to determine the phytochemical composition and the antioxidant potential of extracts (aqueous, ethanolic and ethyl acetate macerates) of S. birrea leaves, bark and roots. Thus, a screening based on qualitative techniques was carried out. The total polyphenols were quantified using the Folin-Ciocalteu method, while the flavonoids were quantified using aluminum trichloride. The in vitro antioxidant activity was determined by the DPPH and Phosphomolybdate tests. The phytochemical screening revealed the presence of alkaloids, tannins, flavonoids, coumarins and terpenoids in all extracts. The ethanolic root extracts showed the highest levels of polyphenols (822.6±36.9 mg GAE/g) and flavonoids (112.59±12.29 mg QE/g). As for the antioxidant potential, the ethanolic extracts of bark showed the best DPPH radical reduction capacity, with an IC50 of 65.57±2.32 µg/mL and a total antioxidant capacity of 882.50±25 mg EAA/g. This study showed that S. birrea organs are a potential source of natural antioxidants that could play a crucial role in the management of hypertension.
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Mamadou A. Konaré, Hadiza Bawa Ibrahim, Fanta Sanogo, Cheickna Cisse, Issiaka Togola, Nouhoum Diarra, 2024. Phytochemistry and antioxidant activity of Sclerocarya birrea extracts, A plant used in the traditional management of hypertension in Mali. Int. J. Biosci., 25(2), 75-82.
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