Prevalence of dengue infection in Delta State, Nigeria
Paper Details
Prevalence of dengue infection in Delta State, Nigeria
Abstract
Dengue fever, a mosquito-borne viral infection caused by the dengue virus, remains an emerging public health concern in many parts of Nigeria where it is often underdiagnosed and underreported. This study aimed to determine the prevalence of dengue virus among febrile patients attending hospitals at Delta State. A total of 400 blood samples were collected from the volunteered participants, fifty (50) samples from each of the eight hospitals selected for the study. Statistical analysis included ANOVA, t-tests and pearsons correlation to assess species association and seasonal trends. Out of 243 individuals examined, 18 (7.4%) tested positive for dengue, while 225 (92.6%) were not infected. Females recorded a higher prevalence of 9.3% compared to 5.3% among males. The difference in infection rates between genders was statistically significant (p = 0.042). During the rainy season, 48 males and 67 females were examined, with 2 (4.2%) male and 7 (10.4%) females testing positive for dengue, while 46 (95.8%) males and 60 (89.6%) females tested negative. In the dry season, 66 males and 62 females were examined, with 4 (6.1%) males and 5 (8.1%) females testing positive, while 62 (93.9%) males and 57 (91.9%) females tested negative. Ute-Okpu recorded the highest infection rate of 16.1%, followed by Agbor (12.9%) and Ughelli (9.7%), while no dengue infection was detected in Abraka. The study revealed generally poor awareness, as only 27.6% were aware of dengue fever, while most (72.4%) lacked knowledge of the disease. Molecular analyses revealed that out of the total sample size 18 (7.4%) were seropositive to dengue immunoglobulins. The four serotypes of dengue D1 – D4 were all detected both during the rainy and dry season. Overall, the results underscore a pressing need for strengthened public health interventions, improved sanitation, sustained vector control measures, and routine arboviral surveillance to reduce the burden of these infections.
Adekola HA, Agu GC, Odeyemi FA, Egberongbe HO, Onajobi IB, Kareem WA, Adejonwo OO. 2024. Seroprevalence of dengue and hepatitis B infections among young adults attending a secondary health care facility at Olabisi Onabanjo University, Ogun State, Nigeria. Proceedings of the Nigerian Academy of Science 17(1), 95–102.
Afolabi BM, Amajoh CN, Adewole TA, Salako LA. 2006. Seasonal and temporal variations in the population and biting habit of mosquitoes on the Atlantic coast of Lagos, Nigeria. Medical Principles and Practice 15(3), 200–208.
Ahmadu SM, Odekunle BO, Chinedu IN, Hussain AA, Biobelu A, Adekanye UA. 2020. Prevalence and determinants of dengue virus immunoglobulin among febrile patients attending Naval Medical Centre Victoria Island, Lagos State. Global Biosecurity 3(1), 32–38.
Ahmed HA, Aweis DMI, Shil GD. 2025. The prevalence of dengue fever among outpatients with clinically suspected acute febrile illness attending Kalkaal Hospital in Mogadishu, Somalia. Saudi Journal of Pathology and Microbiology 10(4), 34–38.
Asaga Mac P, Tadele M, Nisansala T, Airiohuodion PE, Babalola CM, Anyaike C. 2024. An undetected expansion, spread, and burden of chikungunya and dengue cocirculating antibodies in Nigeria. Zoonotic Diseases 4(3), 201–213.
Bhatt P, Sabeena SP, Varma M, Arunkumar G. 2020. Current understanding of the pathogenesis of dengue virus infection. Current Microbiology 78(1), 17–32.
De Araújo Lobo JM, Mores CN, Bausch DG, Christofferson RC. 2016. Serological evidence of under-reported dengue circulation in Sierra Leone. PLOS Neglected Tropical Diseases 10, 21–44.
Ede EL, Egwunyenga AO. 2017. Prevalence of parasitic helminths from faecal samples of cattle at various abattoirs in Abraka, Delta State, Nigeria. Journal of Animal Health and Behavioural Science 1(3), 107.
Emeribe AU, Abdullahi IN, Isong IK, Emeribe AO, Nwofe JO, Shuaib BI. 2021. Dengue virus is hyper-endemic in Nigeria from 2009 to 2020: A contemporary systematic review. Infection and Chemotherapy 53(2), 270–284.
Erhenhi AH, Ede EL, Okunbor RA. 2016. Medicinal plants used for the treatment of skin diseases in Edo State, Nigeria. Journal of Medicinal Plants and Herbal Therapy Research 4, 25–29.
Fagbami AH, Onoja AB. 2018. Dengue haemorrhagic fever: an emerging disease in Nigeria, West Africa. Journal of Infection and Public Health 11(6), 757–762.
Jelinek T. 2009. Vector-borne transmission: malaria, dengue, and yellow fever. In Modern infectious disease epidemiology: concepts, methods, mathematical models, and public health, 381–393. Springer, New York.
Leroy E. 2017. La dengue: symptômes, traitement, prévention, où en est-on?. BoD–Books on Demand.
Lu X, Bambrick H, Frentiu FD, Huang X, Davis C, Li Z. 2022. Species-specific climate suitable conditions index and dengue transmission in Guangdong, China. Parasites and Vectors 15(1).
Mboera LE, Sindato C, Mremi IR, Rumisha SF, George J, Ngolongolo R, Kock R. 2021. Socio-ecological systems analysis and health system readiness in responding to dengue epidemics in Ilala and Kinondoni districts, Tanzania. Frontiers in Tropical Diseases 2, 7–38.
Oforka CL, Omotayo AI, Adeleke MA. 2024. Seasonal diversity in mosquito larval ecology and its public health implications in urban slums of Lagos, Nigeria. American Journal of Tropical Medicine and Hygiene 110(3), 448.
Orhewere RDA, Nmorsi OPG, Ede EL. 2023. Prevalence and risk factors of intestinal helminthiasis and lymphatic filariasis (elephantiasis) co-infections in Idumuje-Unor Community, Delta State, Nigeria. International Journal of Biosciences 23(2), 38–46.
Owusu-Asenso CM, Mingle JA, Weetman D, Afrane YA. 2022. Spatiotemporal distribution and insecticide resistance status of Aedes aegypti in Ghana. Parasites and Vectors 15(1), 61.
Oyero OG, Ayukekbong JA. 2014. High dengue NS1 antigenemia in febrile patients in Ibadan, Nigeria. Virus Research 191, 59–61.
Ratnam I, Black J, Leder K, Biggs BA, Matchett E, Padiglione A, Torresi J. 2012. Incidence and seroprevalence of dengue virus infections in Australian travellers to Asia. European Journal of Clinical Microbiology and Infectious Diseases 31(6), 1203–1210.
Raza FA, Ashraf S, Hasnain S, Ahmad J, Iqbal M. 2018. Dengue seroprevalence and its socioeconomic determinants in Faisalabad, Pakistan: a cross-sectional study. Revista da Sociedade Brasileira de Medicina Tropical 51(4), 503–507.
Sedda L, Ana Paula PV, Eric RG, Rocha A, Caio Henrique P, André Nicolau AG. 2018. The spatial and temporal scales of local dengue virus transmission in natural settings: A retrospective analysis. Parasites and Vectors 11(1), 79.
Tizhe DT, Kwaga JKP, Nok Kia GS. 2022. Serological and molecular survey for dengue virus infection in suspected febrile patients in selected local government areas in Adamawa State, Nigeria. Vaccines 10(9), 1407.
WHO. 2019. Dengue vaccine: WHO position paper, September 2018 – recommendations. Vaccine 37(35), 4848–4849.
P. A. Agbure, O. P. G. Nmorsi, A. O. Egwunyenga, 2025. Prevalence of dengue infection in Delta State, Nigeria. Int. J. Biosci., 27(6), 82-90.
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