home icon user icon
Welcome to International Network for Natural Sciences | INNS Pub.
Home My Account
Submit Manuscript
double_slash
breadcumb_bg

Serum C-reactive protein and fasting glucose in response to moderate aerobic training program in overweight or obese women

Paper Details

Research Paper 01/04/2013
Views (490) Download (13)
current_issue_feature_image
publication_file

Serum C-reactive protein and fasting glucose in response to moderate aerobic training program in overweight or obese women

Hakimi Azadeh, Karami Nasim, Khaled Ismail Raana, Kazemloo Monireh
J. Bio. Env. Sci.3( 4), 95-101, April 2013.
Certificate: JBES 2013 [Generate Certificate]
Key: C-reactive proteinGlucoseLong-term exerciseObesity

Abstract

Obesity is associated with increased chronic inflammatory disease and high risk of cardiovascular disease morbidity or mortality. The objective of present study was to evaluate the effect of 3 months aerobic training on high sensitivity C-reactive protein (CRP) and fasting glucose in non-trained middle-aged women. For this purpose, pre and post training (12 weeks/3 times weekly) of fasting serum CRP and glucose concentration were measured in thirty four non-trained women (aged 37.59 ± 5.36 years; body mass index 31.78 ± 2.86 kg/m2) that divided into control and exercise groups by randomly. Student’s paired ‘t’ test was applied to compare the pre and post training values. Serum CRP levels were significantly decreased in response to exercise program when compared with baseline levels. Compared to pre-training, all anthropometrical markers decreased and fasting glucose concentration decreased significantly after exercise program in the exercise but not in the control groups. Change in serum was positively correlated with change in glucose concentration (p = 0.002, r = 0.69). According to the findings, we conclude that aerobic training for long time improves serum CRP and fasting glucose in overweight or obese women an their changes are dependent of each other.

VIEWS 12
Cover PDF

Black S, Kushner I, Samols D. 2004. C-reactive protein. Journal of Biological Chemistry 279, 48487– 90.

Calabro P, Chang DW, Willerson JT. 2005. Release of C-reactive protein in response to inflammatory cytokines by human adipocytes: linking obesity to vascular inflammation. Journal of the American College of Cardiology 46, 1112–3.

Campbell KL, Campbell PT, Ulrich CM, Wener M, Alfano CM, Foster-Schubert K, Rudolph RE, Potter JD, McTiernan A. 2008. No Reduction in C – reactive protein following a 12-Month Randomized Controlled Trial of Exercise in Men and Women. Cancer Epidemiology, Biomarkers & Prevention 17(7), 1714-8.

Casas JP, Shah T, Hingorani AD. 2008. C-reactive protein and coronary heart disease: a critical review. Journal of General Internal Medicine 264, 295–314.

Eizadia M, Khorshidi D, Seyedhoseini MA, Dooaly H. 2011. Increased interleukin-6 is associated with low cardiorespiratory fitness in healthy people. Journal of Biodiversity and Environmental Sciences 1(4), 48-54.

Eizadib M, Khorshidi D, Dooaly H, Samarikhalaj H. 2011. Circulating adiponectin regulates serum C – reactive protein and Interleukine-6 in obesity. Journal of Biodiversity and Environmental Sciences 1(5), 89-96.

Gillman  B,  Papachristodoulou  DK,  Thomas JH.  2000.  Will’s  Biochemical  Basis  of  Medicine. Oxford: Butterworth Heinemann 4, 343-444.

Grimble RF. 2003. Inflammatory response in the elderly. Current Opinion in Clinical Nutrition and Metabolic Care 6, 21–29.

Hong J, Gu W, Zhang Y, Yang Y, Shen C, Xu M, Li X, Wang W, Ning G. 2007. The interplay of insulin resistance and beta-cell dysfunction involves the development of type 2 diabetes in Chinese obeses. Endocrine 31, 93–99.

Moreno-Aliaga MJ, Lorente-Cebrián S, Martínez JA. 2010. Regulation of adipokine secretion by n-3 fatty acids. Proceedings of the Nutrition Society 69(3), 324-32.

Moschen AR, Molnar C, Geiger S, Graziadei I, Ebenbichler CF, Weiss H. 2010. Anti-inflammatory effects of excessive weight loss: potent suppression of adipose interleukin 6 and tumour necrosis factor {alpha} expression. Gut [Epub ahead of print].

Ouchi N, Kihara S, Funahashi T. 2003. Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue. Circulation 107, 671–4.

Pearson TA, Mensah GA, Alexander RW. 2003. Markers of inflammation and cardiovascular disease: application to clinical and public health practice: a statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association. Circulation 107, 499– 511.

Pepys MB, Hirschfield GM. 2003. C-reactive protein: a critical update. Journal of Clinical Investigation 111, 1805–12.

Petersen AM, Pedersen BK. 2006. The role of IL-6 in mediating the anti-inflammatory effects of exercise. Journal of Physiology & Pharmacology 10, 43-51.

Reuben DB, Cheh AI, Harris TB, Ferrucci L, Rowe JW, Tracy RP, Seeman TE. 2002. Peripheral blood markers of inflammation predict mortality and functional decline in high-functioning community-dwelling older persons. Journal of the American Geriatrics Society 50, 638–644.

Reuben DB, Cheh AI, Harris TB, Ferrucci L, Rowe JW, Tracy RP. 2002. Peripheral blood markers of inflammation predict mortality and functional decline in high-functioning community-dwelling older persons. Journal of the American Geriatrics Society 50, 638–644.

Saghizadeh M, Ong JM, Garvey WT, Henry RR, Kern PA. 1996. The expression of TNF alpha by human muscle. Relationship to insulin resistance. Journal of Clinical Investigation 97, 1111–1116.

Szmitko PE, Wang CH, Weisel RD. 2003. New markers of inflammation and endothelial cell activation: part I. Circulation 108, 1917–1923.

Tarmast D, Zand A, Faraji G, zyaei A. 2012. Hs.C-Reactive Protein is affected by long term aerobic exercise in asthma subjects. International Journal of Biosciences 2(6), 159-164.

Trayhurn P, Wood IS. 2004. Adipokines: inflammation and the pleiotropic role of white adipose tissue. British Journal of Nutrition 92, 347– 355.

Utzschneider K, Prigeon R, Carr D, Hull R, Tong J, Shofer J, Retzlaff B, Knopp R, Kahn S. 2006. Impact of differences in fasting glucose and glucose tolerance on the hyperbolic relationship between insulin sensitivity and insulin responses. Diabetes Care 29, 356–362.

Submit Manuscript