Spatial patterns and prevalence of Hepatitis C virus in Punjab during 2010-2017
Paper Details
Spatial patterns and prevalence of Hepatitis C virus in Punjab during 2010-2017
Abstract
The upsurge of contemporary urbanization has created potential risks for the emergence of infectious diseases like HCV affecting millions of people around the globe. The present research studied the spatial patterns of HCV and its prevalence in the Punjab province for the years 2010, 2013 and 2017. Secondary data sources were used, and district-wise figures of HCV patients were obtained from Directorate of General Health Services Punjab, Health Department Lahore (DGHSP). The data for population was attained from Punjab Bureau of Statistics, Lahore. The collected data were processed and analysed in Microsoft Excel 365 and SPSS 22 for calculating HCV prevalence rate. The spread and major clusters of HCV were shown through maps using ArcGIS 10.5. The results show that HCV has gradually increased in number and expanded in spatial spread within the study area since 2010 and the concentration of disease is found in the north eastern, eastern and central districts of Punjab. Most affected districts are Multan, Lahore, Faisalabad, Toba Tek Singh, Bahawalpur, Sahiwal and Gujranwala. Highest prevalence rate of HCV is found in Multan district with 3.39% hence, all other districts have HCV prevalence rate less than 1%. The study suggests future studies to identify the possible environmental risk factors responsible for the spread of disease in the highly affected districts of Punjab and examine the disease pattern through popular mapping techniques like using hot spot analysis and interpolation method.
Alirol E. 2011. Urbanization and infectious diseases in a globalized world. The Lancet Infectious Diseases 11(2), 131-141. https://doi:10.101016/S1473-3099(10)70223-1
Alter H, Jett B, Polito A. 2011. Hepatitis C: The end of the beginning and possibly the beginning of the end. Annals of International Medicine 154(4), 316-319.
Arden BW. 2008. Medical Geography in Public Health and Tropical Medicine: Case Studies from Brazil. 4th edition, Mc Graw-Hill, New York, USA, 450 pages.
Arshad A, Ashfaq UA. 2017. Epidemiology of hepatitis C infection in Pakistan: current estimate and major risk factors. Critical Reviews in Eukaryotic Gene Expression 21(7), 63-77. https://doi:10.1615/CritRevEukaryotGeneExpr.2017018953
Daw MA, Ali LAB, Daw AM, Sifennasr NEM, Dau AA, Agnan MM. 2018. The Geographic variation and spatiotemporal distribution of hepatitis C virus infection in Libya: 2007–2016. Infectious Diseases 18(1), 1-10.
Khan N, Akmal M, Hayat M, Umar M, Ahmed I, Rahim K, Ali S, Bahadar S, Saleha S. 2014. Geographic distribution of hepatitis C virus genotypes in Pakistan. Hepatitis Monthly 14(10), 202-209.
Mujeeb SA, Sahab S, Hyder AA. 2000. Geographical distribution of health information: study of hepatitis C infection. Pakistan. Public Health 14(1), 413-415.
Petruzziello A, Marigliano S, Loquercio G, Cozzlino A, Cacciapuoti C. 2016. Global epidemiology of hepatitis C virus infection: an up-date of the distribution and circulation of hepatitis C virus genotypes. World Journal of Gastroenterology 22(34), 7824–7840.
Umer M, Iqbal M. 2016. Hepatitis C virus prevalence and genotype distribution in Pakistan: comprehensive review of recent data. World Journal of Gastroenterology 22(4), 1684-1700.
Waller A, Gotway A. 2004. Applied spatial statistics for public health data. 3rd edition, John Wiley & Sons, New York, USA, 325 pages.
Kauhl B, Heil J, Hoeb CJ, Schweikart J, Krafft T, Dukers-Muijrers NH. 2015. The spatial distribution of hepatitis C virus infections and associated determinants: an application of a geographically weighted Poisson regression for evidence-based screening interventions in hotspots. PLOS One 10(1), 1-19. https://doi:10.1371/journal.pone.0135656. eCollection 2015
Wang L, Xing J, Chen F, Yan R, Ge L, Qin Q, Wang L, Ding Z, Guo W, Wang N. 2014. Spatial analysis on hepatitis C virus infection in mainland China: from 2005 to 2011. PLOS One 9(1), 110-119. https://doi:10.1371/journal.pone.0110861
WHO. 2017. Pakistan tackles high rates of hepatitis from many angles. Feature Stories, World Health Organization, Geneva, Switzerland.
WHO. 2019. Hepatitis C, Fact sheets. World Health Organization, Geneva, Switzerland.
Shaista Manaf, Ibtisam Butt, 2019. Spatial patterns and prevalence of Hepatitis C virus in Punjab during 2010-2017. Int. J. Biosci., 15(4), 144-152.
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