Study on phytochemical constituents and antibacterial activity of Mimusops elengi L.
Paper Details
Study on phytochemical constituents and antibacterial activity of Mimusops elengi L.
Abstract
Mimusops elengi L. is an important aromatic herb of the family Sapotaceae which is routinely grown as a traditional medicinal herb in India. In this phytochemical compounds investigation terpenoids, steroids, flavonoids, tannins, phlobatannins and cardiac glycosides showed positive results and saponin showed negative results in aqueous extract. Phytochemical constituents were analysed by FT-IR Spectroscopic method. The FT-IR spectrum was used to identify the functional group of the active components based on the peak value in the region of infrared radiation. Soxhlet apparatus were used for extracting antibacterial active compounds from the plant leaves powered. The discs were prepared and immersed in various solvent extracts. Antibacterial activity was analysed against some clinical pathogens such as Alcaligenes faecalis, Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus and Streptococcus pyogenes. Chloroform and methanol extracts were most effective followed by other water extract. Streptococcus pyogenes and Escherichia coli were more sensitive for Chloroform and methanol extract of leaves of the tested plants. Aqueous extracts low inhibition against the tested organism compared to other test plant extracts.
Alade PI, Irobi ON. 1993. Antimicrobial activities of crude leaf extracts of Acalypha wilkensiana. Journal of Ethnopharmacology 39, 171-174.
Annie Pritima R, Selvaraj Pandian R. 2008. Antimicrobial activity of Coleus aromaticus (benth) against microbes of reproductive tract infections among women. African Journal of Infectious Diseases 1, 18–24.
Balandrin MF, Klocke JA, Wurtele ES, Bollinger WH. 1985. Natural plant chemicals: Sources of industrial and medicinal materials. Science 228, 1154-1160.
Bauer AW, Kirby WMM, Sherries Durk M. 1966. Antibiotic susceptibility testing by a standard single disc method. American Journal of Clinical Pathology 36, 493-496.
Bharat G, Parabia MH. 2010. Pharmacognostic evaluation of bark and seeds of Mimusops elengi Linn. International Journal of Pharmacy and Pharmaceutical Sciences 2, 110-113.
Borris RP. 1996. Natural products research: Perspectives from a major pharmaceutical company. Journal of Ethnopharmacology 51, 29–38.
Britto JS. 2001. Comparative antibacterial activity study of Solanum incanum L. The Journal of the Swamy Botanical Club 18, 81-82.
Bushra Beegum NR, Ganga Devi T. 2003. Antibacterial activity of selected seaweeds from Kovalam south west coast of India. Asian Journal of Microbiology, Biotechnology and Environmental Science 5, 319-322.
Castillo RAM, Gonzalez VP. 1999. Antibacterial effects of Plectranthus amboinicus (Lour.) Spreng (Lamiaceae) in methicillin resistant Staphylococcus aureus (MRSA). Revista Cubana de Plantas Medicinales 3, 110-115.
Cowan MM. 1999. Plant products as antimicrobial agents. Clinical Microbiology Reviews 12, 564-582.
Diallo D, Hveem B, Mahmoud MA, Betge G, Paulsen BS, Maiga A. 1997. An ethnobotanical survey of herbal drugs of Gourma district, Mali. Pharmaceutical Biology 37, 80-91.
Gehlot F, Bohra A. 2000. Antibacterial effect of extract on Salmonella typhi. Indian Journal of Medical Sciences 54, 102-105.
Hamburger M, Hostettmann K. 1991. Bioactivity in plants: The link between phytochemistry and medicine. Phytochemistry 30, 3864-3874.
Harborne JB. 1973. Phytochemical methods. London, Chapman and Hall, Ltd. p. 49-188.
Lin CC, Huang PC. 2000. Antioxidant and hepatoprotective effects of Acanthopanax senticosus. Phytotherapy Research 14, 489–494.
Mohanasundari C, Natarajan D, Srinivasan K, Umamaheswari SA, Ramachandran A. 2007. Antibacterial properties of Passiflora foetida L. a common exotic medicinal plant. African Journal of Biotechnology 6, 2650-2653.
Muhammad HS, Muhammad S. 2005. The use of Lawsonia inermis Linn. (Henna) in the management of burn wound infections. African Journal of Biotechnology 9, 934-937.
Nogueira JCR, Diniz MFM, Lima EO. 2008. In vitro antimicrobial activity of plants in acute otitis. Revista Brasileira de Otorrinolaringologia 74, 118-124.
Oliveira RAG, Torres AR, Diniz MFFM, Araujo EC. 2005. Survey on the use medicinal plants in children hospitalized in the city of Joao Pessoa city: Risks and benefits. Brazilian Journal of Pharmacognosy 15, 373-380.
Perry EK, Pickering AT, Wang WW, Houghton PJ, Perry NS. 1999. Medicinal plants and Alzheimer’s disease: From ethnobotany to phytotherapy. Journal of Pharmacy and Pharmacology 51, 527–534.
Simoes RM, Teixeira D, Maldonado EP, De RW, Zezell DM. 2002. Effects of 1047-nm neodymium laser radiation on skin wound healing. Journal of Clinical Laser Medicine and Surgery 20, 37-40.
Sivakumar R, Alagesaboopathi C. 2006. Antimicrobial activity of two different forms of Abrus precatorius L. Advances in Plant Science 19, 409-413.
Sofowora A. 1993. Medicinal plants and traditional medicines in Africa. Chichester, John Wiley & Sons New York. 97-145p.
Trease GE, Evans WC. 1989. Textbook of pharmacognosy. 14th ed. W.B. Sanders, London. 166-174p.
Warrier PK, Nambiar VP, Ramankutty C. 1995. Indian medicinal plants. 1st ed. Orient Longman Limited, Madras. 315p.
Zar JH. 1984. Biostatistical analysis. Englewood Cliffs, N.J.: Prentice Hall, Inc. 437-467p.
S. Jamuna Devi, L. Prince (2024), Study on phytochemical constituents and antibacterial activity of Mimusops elengi L.; IJB, V25, N1, July, P229-235
https://innspub.net/study-on-phytochemical-constituents-and-antibacterial-activity-of-mimusops-elengi-l/
Copyright © 2024
By Authors and International
Network for Natural Sciences
(INNSPUB) https://innspub.net
This article is published under the terms of the
Creative Commons Attribution License 4.0