The effect of intermittent training on ghrelin and leptin in overweight female students
Paper Details
The effect of intermittent training on ghrelin and leptin in overweight female students
Abstract
Increasing prevalence of obesity and its related diseases are the proper strategies in weight loss and it needed the recognition of the effective factors in weight gaining. Recently, the researchers have discovered some hormones, including ghrelin and leptin witched active the regulating of the energy balance and finally in regulating the body weight. The present study is to determine the effect of intermittent training on Ghrelin and leptin in overweight female students. Twenty overweight female students subject (BMI ≥ 25) were randomly assigned to two groups (intermittent training and control). The experimental training programs were performed three days a week for 12 weeks at a definite intensity and distance. Before and after 12 weeks intervention, Ghrelin, Leptin, weight and body composition, Vo2max was measured for all subjects. For statistical data analysis, the independent t-test of α=0.05 was applied. The result showed that intermittent training caused a significant increase in Ghrelin and Vo2max, significant decrease in Leptin, weight and body composition of the experimental group in comparison to control group. Apparently, intermittent training not only reduces the fat mass but also impacts the secretion of leptin. However, intermittent training increases ghrelin, followed by reduce in the weight loss.
Aminian-Razavi T, Gaeni A, Ravasi AA, Daryanosh F. 2007. The Effect of Two Methods of Alternative and Continuative Exercise on Changing Leptin in Non-Athlete Students of Tehran University. Harakat 31, 57- 69.
Benatti FB, Junior AH. 2007. Leptin and endurance exrcise: implications of adiposity and insulin. Revista Brasileira de Medicina do Esporte 13 (4), 239E- 244E.
Broom, DR, Stensel DJ, Bishop NC, Burns SF, Miyashita M. 2007. Exercise- induced suppression of acylated ghrelin in humans. Journal of Applied Physiology 102(6), 2165-2171. http://dx.doi.org/10.1152/japplphysiol.00759.2006
Cummings DE, Weigle DS, Frayo RS, Breen PA, Ma MK, Dellinger EP, Purnell JQ. 2002. Human plasma ghrelin levels after diet-induced weight loss and gastric bypass surgery. New England Journal of Medicine 346(21), 1623–1630. http://dx.doi.org/10.1056/NEJMoa012908
Dall R, Kanaley J, Hansen TK, Moller N, Christiansen JS, Hiroshi Hosoda H, et al. 2002. Plasma ghrelin levels during exercise in healthy subjects and in growth hormone- deficient patients. European Journal of Endocrinology 147, 65–70. http://dx.doi.org/10.1530/eje.0.1470065
Fatouros IG, Tournis S, Leontsini D, Jamurtasn AZ, Sxina M, Thomakos P, et al. 2005. Leptin and adiponectin responses in overweight inactive elderly following resistance training and detraining are intensity related”. Journal of Clinical Endocrinology & Metabolism 90, 5970-77. http://dx.doi.org/10.1210/jc.2005-0261
Foster – Schubert KE, McTiernan A, Frayo RS, Schwartz RS, Rajan KB, Yasui Y, Tworoger SS, Cummings DE. 2005. Human plasma ghrelin levels increase during a one – year exercise program. Journal of Clinical Endocrinology & Metabolism 90(2), 820– 825.
Fujimiya M, Asakawa A, Fujino K, Chen C, Inui A. 2006. Acylated ghrelin and des-acyl ghrelin exert different effects on the gastrointestinal motility in conscious rats. International Congress Series 1287, 361- 367. http://dx.doi.org/10.1016/j.ics.2005.11.115
Ghanbari-Niaki A. 2006. Ghrelin and glucoregulatory hormone responses to a single circuit resistance exercise in male college students. Clinical Biochemistry 39(10), 966– 970. http://dx.doi.org/10.1016/j.clinbiochem.2006.05.00 9
Gil-Campos M, Aguilera C, Can RG. 2006. A Ghrelin: a hormone regulating food intake and energy homeostasis. British Journal of Nutrition 96, 201– 226. http://dx.doi.org/10.1079/BJN20061787
Gomez-Merino D, Chennaoui M, Drogou C, Bonneau D, Guezennec CY. 2002. Decrease in serum leptin after prolonged physical activity in men. Medicine and Science in Sports and Exercise 34(10), 1594-1599. http://dx.doi.org/10.1097/00005768-200210000-00010
Haghighi AH, Hamedinia MR. 2008. The effect of 13 aerobic training on leptin obese men. Olampic 1(41), 89- 97.
Hamedinia MR, Porjahed J, Sardar MA, Haghighi AH. 2008. The effect of primary swimming training on leptin serum and related hormones in obese children and adolescents. Human Movement Science 2, 87- 96.
Hansen TK, Dall R, Hosoda H, Kojima M, Kangawa K, Christiansen JS, et al. 2002. Weight loss increases circulating levels of ghrelin in human obesity. Clinical Endocrinology 56(2), 203- 206.
Hayase H, Nomura S, Abe T, Izawa T. 2002. Relation between fat distributions and several plasma adipocytokines alter exercise training in premenopausal and postmenopausal women. Journal of Physiological Anthropology 21(2), 105-113. http://dx.doi.org/10.2114/jpa.21.105
Houmard JA, Cox JH, Paul S. MacLean PS, Barakat HA. 2000. Effect of short-term exercise training on leptin and insulin action. Metabolism 49(7), 858– 861. http://dx.doi.org/10.1053/meta.2000.6751
Hsu Y, Wang P. 2007. Change of active ghrelin, leptin and female endocrine profiles at late follicular phase during 1 month endurance training in the chinese population”. Biology of Reproduction 77, 104–104.
Imai T, Aizawa K, Hyun M, Iida K, Mural F, Kono I, et al. 2009. Acute effects of resistance exercise on adiponectin and leptin. Sports Medicine 58(2), 239- 246.
Karen JA, Lorentzen C, Anderssen SA, Birkeland KI, Holme I, Lund-Larsen PG, Ommundsen Y, Raastad T, Thelle DS, Bahr R. 2004. Promoting physical activity in a multi-ethnic district – methods and baseline results of a pseudo-experimental intervention study. European Journal of Cardiovascular Prevention & Rehabilitation 10(5), 387-396.
Kim HJ, Lee S, Kim TW, Kim HH, Jeon TY, Yoon YS et al. 2008. Effects of exercise-induced weight loss on acylated and unaclated ghrelin in overweight children. Clinical Endocrinology 68(3), 416- 422.
Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K. 1999. Ghrelin is a growth– hormone- releasing acylated peptide from stomach. Nature 402, 656–660. http://dx.doi.org/10.1038/45230
Kojima M, Kangawa K. 2005. Ghrelin: Structure and function. Physiological Reviews 85(2), 495-522. http://dx.doi.org/10.1152/physrev.00012.2004
Kopelman PG. 2000. Obesity as a medical problem. Nature 404(6778), 635–64.
Koutsari C, Karpe F, Humphreys SM, Frayn KN, Hardman AE. 2003. Plasma leptin is influenced by diet composition and exercise. International Journal of Obesity 27, 901- 906. http://dx.doi.org/10.1038/sj.ijo.0802322
Kraemer RR, Chu H, Castracane VD. 2002. Leptin and exercise. Experimental Biology and Medicine 227(9), 701–708.
Kraemer RR, Durand RJ, Acevedo EO, Johnson LG, Kraemer GR, Hebert EP, Castracane VD. 2004. Rigorous running increases growth hormone and insulin like growth factor-1 without altering ghrelin. Experimental Biology and Medicine 229(3), 240–6.
leidy HJ, Gardner JK, Frye BR, Snook ML, Schuchert MK, Richard EL, Williams NI. 2004. Circulating ghrelin is sensitive to changes in body weight during a diet and exercise program in normal-weight young women. Journal of Clinical Endocrinology & Metabolism 89(6), 2659-64.
Marzullo P, Verti B, Savia G, Walker GE, Guzzaloni G, Tagliaferri M et al. 2004. The relationship between active ghrelin levels and human obesity involves alterations in resting energy expenditure. Journal of Clinical Endocrinology & Metabolism 89(2), 936-939. http://dx.doi.org/10.1210/jc.2003-031328
Mirzaei B. Irandoust KH, Rahmani-Nia F, Mohebbi H, Hassan-Nia S. 2009. Unacylated ghrelin levels increase after aerobic exercise program in obese women. Brazilian Journal Biomotricity 3(1), 11-20.
Ning Y, Williams MA, Butler CL, Muy-Rivera M, Frederick IO, Sorensen TK. 2005. Maternal recreational physical activity is associated with plasma leptin concentrations in early pregnancy. Human Reproduction 20(2), 382-389. http://dx.doi.org/10.1093/humrep/deh615
Rahmani Nia F, Hojjati Z, Rahnama N, Soltani B. 2009. Leptin, Heart Disease and Exercise. World Journal of Sport Sciences 2(1), 13-20.
Robert R. Kraemer V, Castracane D. 2007. Exercise and humoral mediators of peripheral energy balance: ghrelin and adiponectin. Experimental Biology and Medicine 232, 184–194.
Schmidt A, Maier C, Schaller G, Nowotny P, Bayerle-Eder M, Buranyi B, Luger A, Wolzt M. 2004. Acute exercise has no effect on ghrelin plasma concentrations. Hormone Metabolic Research Journal 36(3), 174 –177. http://dx.doi.org/10.1055/s-2004-814342
Tritos Na, Maratos-Flier E. 1999. Two important systems in energy homeostasis: melanocortins and melanin concentrating hormone. Neuropeptide 33(5), 339-49. http://dx.doi.org/10.1054/npep.1999.0055
Tsao TH, Hsu CH, Yang CB and Liou TL. 2009. The effect of exercise intensity on serum leptin and C-reactive protein levels. Journal of Exercise Science and Fitness 7(2), 98– 103. http://dx.doi.org/10.1016/S1728-869X(09)60012-5
Tschop M, Smiley DL, Heiman ML. 2000. Ghrelin induces adiposity in rodents. Nature 407, 908– 913. http://dx.doi.org/10.1038/35038090
Unal M, Unal DO, Baltaci AK, Mogulkoc. 2005a. Investigation of serum leptin levels and VO2max value in trained young male athletes and healthy males. Acta Physiology Hungary 92(2), 173- 179. http://dx.doi.org/10.1556/APhysiol.92.2005.2.8
Unal M, Unal DO, Baltaci AK, Mogulkoc R, Kayserilioglu A. 2005b. Investigation of serum leptin levels in professional male football players and healthy sedentary males. Neuro Endocrinology Letters 26(2), 148-151.
Wang J, Chen C, Wang RY. 2008. Influence of short- and long-term treadmill exercises on levels of ghrelin, obestatin and NPY in plasma and brain extraction of obese rats. Endocrine Journal 33(1), 77-83. http://dx.doi.org/10.1007/s12020-008-9056-z
Sohaily Shahram, Yadegari Elham, Faraji Gholamreza, Zand Alireza (2013), The effect of intermittent training on ghrelin and leptin in overweight female students; IJB, V3, N8, August, P347-355
https://innspub.net/the-effect-of-intermittent-training-on-ghrelin-and-leptin-in-overweight-female-students/
Copyright © 2013
By Authors and International
Network for Natural Sciences
(INNSPUB) https://innspub.net
This article is published under the terms of the
Creative Commons Attribution License 4.0