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Anti-inflammatory, antipyretic and analgesic activities of ethanol extract of Eugenia jambolana Lam

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Research Paper 01/03/2020
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Anti-inflammatory, antipyretic and analgesic activities of ethanol extract of Eugenia jambolana Lam

S. Alyas, N. Zahra, N. Zahid, A. Nisar, MI. Ahmad
Int. J. Biosci.16( 3), 493-498, March 2020.
Certificate: IJB 2020 [Generate Certificate]
Key: AnalgesicAnti-inflammatoryAntipyreticEugenia jambolanaleafStem

Abstract

The aim of present study is to determine anti-inflammatory, antipyretic and analgesic activities of ethanolic extract of Eugenia jambolana Lam. Plant of Eugenia is commonly used to treat different diseases like fever, pain and inflammation. A total of 144 albino rats with average weight of 200g were used in this study. Rats were divided into 4 groups each group contained 12 rats. Anti-inflammatory activity was evaluated by 0.1mL of 1% carrageenan extract that induce paw edema while analgesic activity was investigated by acetic acid that induce abdominal writhing response whereas, antipyretic activity was demonstrated by yeast that induce pyrexia in rats. In anti-inflammatory, antipyretic and analgesic activities, significant results were shown at 400mg/kg and 50mg/kg dose respectively in multiple comparisons. There was significant (p<0.005) decrease in inflammation, pyrexia and writhing. The stem extract of E. jambolana lam showed significant result as compare to leaf extract in anti-inflammatory and analgesic activity.

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