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Phenotypic profiles of nosocomial Staphylococcus aureus isolates of Iligan City, Philippines

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Research Paper 01/07/2018
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Phenotypic profiles of nosocomial Staphylococcus aureus isolates of Iligan City, Philippines

Lucilyn L. Maratas, Muriel Faith A. Goles
Int. J. Biosci.13( 1), 117-121, July 2018.
Certificate: IJB 2018 [Generate Certificate]
Key: Antibiotic resistanceCLSINosocomial strainsStaphylococcus aureus

Abstract

The increase of resistance of Staphylococcus aureus against commonly used antibiotics is perceived as a threat in therapeutic fields. The present study investigates the susceptibility of nosocomial strains of S. aureus against four major antibiotics: erythromycin, clindamycin, oxacillin and vancomycin. Ninety-four previously identified S. aureus nosomonial isolates were reconfirmed following the standard microbiological procedures for the isolation and identification of S. aureus: cultural, morphological and biochemical characterizations. Antibiograms of all isolates were determined employing the current guidelines of the Clinical and Laboratory Standards Institute (CLSI) on Müeller Hinton Agar. The resistance phenotypes were highest against clindamycin at 51% (48 isolates), making it the least effective antibiotic. Resistance against oxacillin and erythromycin were 46% (43 isolates) and 38% (36 isolates), respectively. The results indicated that the isolates are still susceptible to vancomycin which has the lowest resistance at 4% (4 isolates), making it the most effective antibiotic.

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