Quantification of phenolic compounds of wild plants Pulicaria gnaphalodes and their antimicrobial activity
Paper Details
Quantification of phenolic compounds of wild plants Pulicaria gnaphalodes and their antimicrobial activity
Abstract
The current study was used to determine the antioxidant potential of aqueous methanolic extracts of roots of Pulicaria gnaphalodes and quantified the bioactive compound through HPLC. The aqueous methanolic extract of roots recorded the highest total polyphenols content (TPC) 41.56 mg GAE/g of DM and total flavonoid contents (TFC) 29.58 mg QE/g of DM. Results showed that maximum DPPH free radical scavenging activity and reducing power was observed with an aqueous methanolic extract about 88% and 1.41 nm absorption respectively. Antibacterial activity of the different extracts showed that most of the bacterial strains tested were sensitive to Pulicaria gnaphalodes extracts.
Abraham J, Thomas TD. 2012. Antibacterial activity of medicinal plant Cyclea peltata (Lam) Hooks & Thoms. Asian Pacific Journal of Tropical Biomedicine 2(4), 280-284. https://doi.org/10.1016/S2222-1808(12)60166-2.
Ahmed D, Khan MM, Saeed R. 2015. Comparative analysis of phenolics, flavonoids, and antioxidant and antibacterial potential of methanolic, hexanic and aqueous extracts from Adiantum caudatum leaves. Antioxidants 4(2), 394-409. https://doi.org/10.3390/antiox4020394.
Amber R, Adnan M, Tariq A, Khan SN, Mussarat S, Hashem A, AbduAllah EF. 2017. Antibacterial activity of selected medicinal plants of northwest Pakistan traditionally used against mastitis in livestock. Saudi Journal of Biological Sciences 8(2), 45-50. https://doi.org/10.1016/j.sjbs.2017.02.008.
Asghari G, Zahabi F, Eskandarian A, Yousefi H, Asghari M. 2014. Chemical composition and leishmanicidal activity of Pulicaria gnaphalodes essential oil. Research Journal of Pharmacognosy 1(4), 27-33. http://rjpharmacognosy.ir.
Bajpai VK, Baek KH, Kang S C. 2017. Antioxidant and free radical scavenging activities of taxoquinone, a diterpenoid isolated from Metasequoia glyptostroboides. South African Journal of Botany 111, 93-98. https://doi.org/10.1016/j.sajb.2017.03.004.
Benslama A, Harrar A. 2016. Free radicals scavenging activity and reducing power of two Algerian Sahara medicinal plants extracts. International Journal of Herbal Medicine 4(6), 158-61. https://doi.org/10.22271/FLORA.2016.V4.I6C.03
Boeing JS, Barizão ÉO, e Silva BC, Montanher PF, de Cinque Almeida V, Visentainer JV. 2014. Evaluation of solvent effect on the extraction of phenolic compounds and antioxidant capacities from the berries: application of principal component analysis. Chemistry Central Journal 8(1), 48. https://doi.org/10.1186/s13065-014-0048-1.
Brand-Williams W, Cuvelier ME, Berset C. 1995. Use of a free radical method to evaluate antioxidant activity. LWT—Food Science and Technology 28, 25–30. https://agris.fao.org/agris-search/search.do?recordID=US201301501652.
Türkoğlu S, Parlak AE. 2014. Aquatik bir bitkinin (Riccia fluitans) toplam fenolik ve toplam flavonoid içeriklerinin ve antioksidan kapasitelerinin belirlenmesi. Ege Journal of Fisheries and Aquatic Sciences 31(1), 77-78. https://doi.org/10.12714/egejfas.2014.31.1.06
Dhawan D, Gupta J. 2017. Comparison of Different Solvents for Phytochemical Extraction Potential from Datura metel Plant Leaves. International Journal of Biological Chemistry 11, 17-22. https://doi.org/10.3923/ijbc.2017.17.22
Halliwell B. 1997. Antioxidants and human diseases: a general introduction. Nutrition Reviews 55, 44–52. https://doi.org/10.1111/j.1753-4887.1997.tb06100.x.
Harbourne JB. 1998. Phytochemical Methods e A Guide to Modern Techniques of Plant Analysis. London: Chapman and Hall; 1998. https://www.springer.com/gp/book/9780412572609
Kamkar A, Ardekani MRS, Shariatifar N, Misagi A, Nejad ASM, Jamshidi AH. 2013. Antioxidative effect of Iranian Pulicaria gnaphalodes L. extracts in soybean oil. South African Journal of Botany 85, 39-43. https://doi.org/10.1016/j.sajb.2012.12.001.
Kumaran A. 2006. Antioxidant and free radical scavenging activity of an aqueous extract of Coleus aromaticus. Food Chemistry 97(1), 109-114. https://doi.org/10.1016/j.foodchem.2005.03.032.
Mickymaray S, Al Aboody MS, Rath PK, Annamalai P, Nooruddin T. 2016. Screening and antibacterial efficacy of selected Indian medicinal plants. Asian Pacific Journal of Tropical Biomedicine 6(3), 185-191. https://doi.org/10.1016/j.apjtb.2015.12.005
Nandhakumar E, Indumathi P. 2013. In vitro antioxidant activities of methanol and aqueous extract of Annona squamosa (L.) fruit pulp. Journal of Acupuncture and Meridian Studies 6(3), 142-148. https://doi.org/10.1016/j.jams.2012.09.002
Pavithra K, Vadivukkarasi S. 2015. Evaluation of free radical scavenging activity of various extracts of leaves from Kedrostis foetidissima (Jacq.) Cogn. Food Science and Human Wellness 4(1), 42-46. https://doi.org/10.1016/j.fshw.2015.02.001.
Riaz M, Rasool N, Bukhari I, Shahid M, Zubair M, Rizwan K, Rashid U. 2012. In vitro antimicrobial, antioxidant, cytotoxicity and GC-MS analysis of Mazus goodenifolius. Molecules 17(12), 14275-14287. https://doi.org/10.3390/molecules171214275.
Senhaji B, Chebli B, Mayad E, Hamdouch A, Heimeur N, Chahid A, Ferji Z. 2017. Phytochemical screening, quantitative analysis and antioxidant activity of Asteriscus imbricatus and Pulicaria mauritanica organic extracts. International Food Research Journal 24(6), 2482-2489. https://doi.org/10.1016/j.fshw.2015.02.001.
Shariatifar N, Kamkar A, Shams AM, Misaghi A, Jamshidi AH, Jahed KG. 2012. Quantitative and qualitative study of phenolic compounds and antioxidant activity of plant Pulicaria gnaphalodes. Ofogh-e Danesh 18, 35–41. http://hms.gmu.ac.ir/browse.php?a_id=1140&sid=1&slc_lang=en.
Sharma P, Sharma JD. 2001. In vitro hemolysis of human erythrocytes—by plant extracts with antiplasmodial activity. Journal of ethnopharmacology 74(3), 239-243. https://www.springer.com/gp/book/9780412230509
Sharma S, Vig AP. 2013. Evaluation of in vitro antioxidant properties of methanol and aqueous extracts of Parkinsonia aculeata L. leaves. The Scientific World Journal 45(35), 235-239. https://doi.org/10.1155/2013/604865.
Stanojević L, Stanković M, Nikolić V, Nikolić L, Ristić D, Čanadanovic-Brunet J, Tumbas V. 2009. Antioxidant activity and total phenolic and flavonoid contents of Hieracium pilosella L. extracts. Sensors 9(7), 5702-5714. https://doi.org/10.3390/s90705702
Sultana B, Anwar F, Ashraf M. 2009. Effect of extraction solvent/technique on the antioxidant activity of selected medicinal plant extracts. Molecules 14(6), 2167-2180. https://doi.org/10.3390/molecules14062167.
Muhammad Bilal, Abdul Ahid Rashid, Ishtique Ahmad, Sheraz Ahmed, Salmaan Saeed, Muhammad Qumar, Muhammad Imran, 2021. Quantification of phenolic compounds of wild plants Pulicaria gnaphalodes and their antimicrobial activity. Int. J. Biosci., 18(1), 15-25.
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