Anti-anemic effect of Thymus vulgaris L. leaves powder on iron deficient rats
Paper Details
Anti-anemic effect of Thymus vulgaris L. leaves powder on iron deficient rats
Abstract
Herbal plants and their active ingredients are becoming more important for natural and safe use as compared to synthetic medications. For this purpose, the pharmacological impact of Thymus vulgaris (thyme) leaves powder to mitigate iron deficiency anemia was observed. Thyme leaves powder was subjected to nutritional analysis. To explore the anti-anemic effect, thyme leaves powder (G1:10 g, G2: 20 g and G3: 30g) was fed to animal subjects. Forty female Sprague Dawley rats were allocated into four groups and each group fed for 6 weeks. The blood samples for serum biochemical parameters, hematological indices as well as liver and kidney function tests were analyzed at intervals of 0, 21 and 42 days. Results revealed that dried thyme leaves powder had high contents of proteins (20.43%), fiber (13.68%), nitrogen free extract (44.05%) as well as mineral contents. Feed intake and body weight gain were increased significantly (p<0.05) in experimental groups. The highest feed intake and body weight gain was observed in G3 i.e. (22.35 ± 0.86 g per rat per day diet) and (112.97 ± 1.28 to 169.91 ± 1.12 g per rat), respectively. Similarly, G3 showed more increase in serum biochemical profile and hematological indices during efficacy study as compared to G1 and G2. Liver and kidney functioning values showed decreasing trend throughout the study period of 42 days. The results of present study conclude that the strong nutritional composition of thyme leaves powder has a safe and therapeutic role against the treatment of iron deficiency anemia.
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Marwa Waheed, Zarina Mushtaq, Muhammad Imran, Muhammad Kamran Khan, Nazir Ahmad, Muhammad Bilal Hussain (2019), Anti-anemic effect of Thymus vulgaris L. leaves powder on iron deficient rats; IJB, V15, N2, August, P503-512
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