Clinico-mycological profile of isolates of superficial fungal infection: A study in a Tertiary care centre in Baster Region
Paper Details
Clinico-mycological profile of isolates of superficial fungal infection: A study in a Tertiary care centre in Baster Region
Abstract
The superficial (cutaneous) fungal infections involve skin and its appendages, hair and nails. The causative fungi colonize only cornified layer of epidermis or supra-follicular portion of hair and usually do not penetrate into deeper tissues. The distribution and frequency of these infections and their etiological agents vary according to the geographic region, the socioeconomic level of population, climatic variation, presence of domestic animals and age. These infections are usually presented as scaly patches with central clearing with sharply demarcated as annular, erythematous, sometimes with vesicles, blisters and pustules. These superficial fungal infections are also responsible for morbidity, affecting quality of life, have recurrent relapses and drug resistance. This study was carried to find out the prevalence of various fungi associated with superficial fungal infection. This is a retrospective observational study carried to see clinical and laboratory profile of clinically suspected cases of superficial (cutaneous) fungal infection cases attending Dermatology Out Patient Department (OPD) and Skin scrapings, hair and nail samples were collected and processed according to standard mycological protocol. A total of 120 specimens were collected from clinically diagnosed superficial fungal infection cases. Tinea corporis was the most common clinical type in our study followed by Pityriasis versicolor, Onycomycosis and Tinea pedis. Most common dermatophyte species isolated was Trichophyton mentegrophyte and Malassezia sp. followed by Trichophyton violaceum, Candida sp., Trichophyton rubrum, Microsporum audouinii and Fusarium sp. Along with dermatophytes, nondermatophytic fungal infections are emerging as important debilitating problems affecting quality of life. Due to different type of antifugal use in different superficial mycoses, laboratory confirmation is desired, to decrease inappropriate use of drugs and drug resistance.
Aggarwal, Usha Arora, Saroj Khanna. 2018. 47 Indian Journal of Dermatology Indian Journal of Dermatology. [publisher not identified]. www.e-ijd.org/asp?issn=0019-5154;year= 2002;volume=47;issue=4;spage=218;epage=220;aulast=Aggarwal;type=0 (April 8, 2018).
Ahearn, Donald G. 1988. “Medical Mycology: The Pathogenic Fungi and the Pathogenic Actinomycetes.” JAMA: The Journal of the American Medical Association 260(12): 1794. http://jama.jamanetwork.com/article.aspx?doi=10.1001/jama.1988.03410120140051 (April 8, 2018).
Ajello, Libero. 1962. “Present Day Concepts of the Dermatophytes.” Mycopathologia et Mycologia Applicata 17(4), 315–24. http://link.springer.com/10.1007/BF02076216 (April 8, 2018).
Aly, Raza. 1975. “Medical Mycology: The Pathogenic Fungi and the Pathogenic Actinomycetes.” Archives of Dermatology 111(4), 544- http://archderm.jamanetwork.com /article.aspx?doi=10.1001/archderm.1975.01630160134035 (April 8, 2018).
Article, Original. 2010. “Prevalence of Dermatophyte Infection in District Rajkot.” 3 (December 2005): 1-3.
Bettley, F. Ray. 1965. “Textbook of Dermatology.” British Medical Journal 1(5428), 178.
Das, Krishnendu, Sukumar Basak, and Subha Ray. 2009. “A Study on Superficial Fungal Infection from West Bengal : A Brief Report.” 1(1), 5155.
Grover, Sanjiv, and P Roy. 2003. “Clinico-Mycological Profile of Superficial Mycosis.
Havlickova, Blanka, Viktor A, Czaika and Markus Friedrich. 2008. “Epidemiological Trends in Skin Mycoses Worldwide.” Mycoses 51, 2-15. http://www.ncbi.nlm.nih.gov/pubmed/1878 3559 (April 8, 2018).
Khadka, Sundar et al. 2016. “Clinicomycological Characterization of Superficial Mycoses from a Tertiary Care Hospital in Nepal.” Dermatology research and practice 2016, 9509705. www.ncbi.nlm.nih.gov/pubmed/28003819
Mathur M, Kedia S, Bk K, Ghimire R. 2018 “"Epizoonosis of Dermatophytosis": A Clinico- Mycological Study of Dermatophytic Infections in Central Nepal.” Kathmandu University medical journal (KUMJ) 10(37), 30-33. www.ncbi.nlm.nih.gov22971858 (April 8, 2018).
Mishra MS Mishra PC, Singh and Mishra BC. 1998. “Clinico-Mycological Profile of Superficial Mycoses.” Indian journal of dermatology, venereology and leprology 64(6), 283–85. www.ncbi.nlm.nih.gov/pubmed/20921797 (April 8, 2018).
Negi, Nidhi, Vibha Tripathi, Reshmi Chanda Choudhury and Jitendra Singh Bist. 2017. “Clinicomycological Profile of Superficial Fungal Infections Caused by Dermatophytes in a Tertiary Care Centre of North India.” 6(8), 3220-27.
Torssander J, et al. 1988. “Dermatophytosis and HIV Infection. A Study in Homosexual Men.” Acta dermato-venereologica 68(1), 53-56. www.ncbi.nlm.nih.gov/pubmed/2449012 (April 8, 2018).
Venkatesan G, et al. 2007. “Trichophyton Rubrum –The Predominant Etiological Agent in Human Dermatophytoses in Chennai , India.” African Journal of Microbiology Research (May) 9-12.
Vishal Jariwala RK, Bansal, Swati Patel, Bimal Tamakuwala. 2010. “A Study of Superficial Mycosis in South Gujarat Region.” National Journal of Community Medicine 1(2), 85-88.
Rupam Gahlot, Chaitanya Nigam, 2018. Clinico-mycological profile of isolates of superficial fungal infection: A study in a Tertiary care centre in Baster Region. Int. J. Microbiol. Mycol., 7(3), 1-5.
Copyright © 2018 by the Authors. This article is an open access article and distributed under the terms and conditions of the Creative Commons Attribution 4.0 (CC BY 4.0) license.