Comparative study of phenolic compound contents and antioxidant potential of Moringa oleifera Lam. leaf extracts from the four climatic zones of Mali

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Research Paper 01/09/2020
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Comparative study of phenolic compound contents and antioxidant potential of Moringa oleifera Lam. leaf extracts from the four climatic zones of Mali

Tahmat Walet Hamata, Issiaka Togola, Lassana Sissoko
Int. J. Biosci.17( 3), 105-113, September 2020.
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Moringa oleifera (MO) due to its medicinal and nutritional virtues has been acclimated in all the climatic zones of Mali. The aim of this work was to evaluate the variation of antioxidant activity of MO leaves harvested in four climatic zones of Mali. Thus, the contents of some important antioxidants compounds (such as total polyphenols and flavonoids) were determined by spectrophotometric method. The evaluation of the antioxidant activity of extracts was done by DPPH method. Some differences have been found between the levels of total polyphenols and flavonoids. The sample from Segou (Sudanian zone) had the highest levels of total polyphenols and flavonoids, while the Sikasso (Sudano-Guinean zone) one had the lowest. In regards to the antioxidant activity is concerned, the Segou sample has been the most active with IC50 = 27.79 ± 0.09 μg/mL; that activity is higher than the standard, ascorbic acid (with IC50 = 36.72 ± 0.11 μg/mL). Samples from Timbuktu (Saharan zone), Mopti (Sahelian zone) and Sikasso showed statistically similar antioxidant activities. This study showed that MO leaves are rich in metabolites and possess a high antioxidant power; that could help to prevent the malnutrition and certain disorders related to oxidative stress.


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