Evaluation of antioxidant and antibacterial activity of Putranjiva roxburghii Wall. fruit peel
Paper Details
Evaluation of antioxidant and antibacterial activity of Putranjiva roxburghii Wall. fruit peel
Abstract
Putranjiva roxburghii Wall. (Euphorbiaceae) has long been used in folk treatment. Considering this folkloric background, this study was designed to evaluate in vitro antioxidant and antibacterial activity of P. roxburghii fruit peel (PRFP) enthanolic (95%) extract. Antioxidant activity was checked based on 2, 2-diphenyl-1- picrylhydrazyl (DPPH) free radical scavenging capacity. Antibacterial aptitude of PRFP was assessed using disc diffusion assay against two bacterial strains Bacillus subtelis and Enterobacter xiangfangensis. Disc diffusion assay was performed with three different PRFP doses (250, 500, and 1000 µg/disc). PRFP showed excellent antioxidant activity with 17.3 µg/mL IC50 (concentration that scavenged 50% DPPH radical) value. In antibacterial test, PRFP inhibited growth both of B. subtelis and E. xiangfangensis by revealing inhibition zone in dose-dependent fashion. Overall, PRFP is a rich source of pharmaceutical agents in terms of antioxidant and antibacterial activity.
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