Green synthesis of silver nanoparticles using Lonicera quinquelocularis leaf extract exhibits antibacterial and antioxidant activities

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Green synthesis of silver nanoparticles using Lonicera quinquelocularis leaf extract exhibits antibacterial and antioxidant activities

Arshya Iqbal, Farmanullah Khan, Syed Badshah, Masood Afzal, Liqun Zhang, Wang Zhao, Kamran Tahir, Fawad Ali, Shafiullah Khan
Int. J. Biosci.10( 5), 116-127, May 2017.
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Nanotechnology is a field that is mushrooming, having an impact in all circles of human life. Nano biotechnology represents an economic alternative for chemical and physical methods of nanoparticles formation. Presently available literature revealed that the NP synthesis using marine plants, microrganisms and algae as source has been unexplored and underexploited. The development of green processes for the synthesis of silver NP is developing into an important branch of nanotechnology. It has many benefits such as, ease with which the process can be scaled up, economic viability (Varahalarao and Kaladhar, 2014). In this study, the novel, one-step biosynthesis of AgNPs using the extract of Lonicera quinquelocularis at room temperature. The aim of this study is to synthesize AgNPs using a green synthesis method. A simple, ecofriendly, low cost and harmless green method have been developed to synthesized silver nanopaticles using Lonicera quinquelocularis leaf extract. The key points of our method were to produce highly dispersed, small size (5-12 nm) and spherical shape silver nanoparticles as compared to other methods.  The biogenic silver nanoparticles exhibited maxima absorbance at 423nm due to surface Plasmon resonance which indicates the formation of silver nanoparticles. These nanoparticles were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), UV-visible spectroscopy (UV-Vis), Energy-dispersive X-ray spectrometry (EDX), high-resolution transmission electron microscopy (HRTEM) and Fourier-transform infrared spectroscopy (FT-IR). Infrared spectral analysis confirmed that Lonicera quinquelocularis leaf extract contains active functional groups which work both as a reducing and stabilizing agent. The strong antioxidant and antibacterial activities of synthesized nanoparticles make them a lead source of therapeutic agent with broad spectrum biological activities. The considerable activities are attributed to the small size, high dispersion of silver nanoparticles and the active constituents of Lonicera quinquelocularis extract.


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