Murraya koenigii (Linn.) Spreng.: An opulent source of fatty acid

Paper Details

Research Paper 15/04/2026
Views (320)
current_issue_feature_image
publication_file

Murraya koenigii (Linn.) Spreng.: An opulent source of fatty acid

Shahin Aziz*
Int. J. Biosci. 28(4), 116-122, April 2026.
Copyright Statement: Copyright 2026; The Author(s).
License: CC BY-NC 4.0

Abstract

Murraya koenigii L., a medicinal plant utilized in traditional folk medicine, possesses anti-diabetic, anti-microbial, anti-inflammatory attributes and also is widely used for the treatment of hemorrhoids, itching, leukoderma, and hematological disorders. From the present work, total 8 fatty acids were identified by Gas Chromatography–Mass PSpectrometry (GC-MS) technique where the level of saturation in the fatty acid derived from the petroleum ether extract of the aerial section of Murraya koenigii L. is significantly higher compared to unsaturated part. The saturated portion includes capric acid, myristic acid, palmitic acid, stearic acid and arachidic acid while palmitic acid is obtained at higher concentration (35.07%). Conversely the unsaturated portion comprises oleic acid, linoleic acid, α-linoleic acid where oleic acid covers a significant concentration (17.31%). In connection to the above findings, the current study indicates that the significant presence of fatty acids such as palmitic acid, oleic acid, α-Linolenic acid may contribute to the recognition of the potential pharmacological significance of this plant in the treatment of illnesses.

Abdelwahab SI, Taha MM. 2023. Global research trends of the studies on Murraya koenigii (L.) Spreng: A Scopus-based comprehensive bibliometric investigation (1965–2023). Bulletin of the National Research Centre 47(1), 138. https://doi.org/10.1186/s42269-023-01113-x

Abhishek M, Dua VK, Prasad GB. 2010. Antimicrobial activity of leaf extracts of Murraya koenigii against aerobic bacteria associated with bovine mastitis. International Journal of Chemical Environmental and Pharmaceutical Research 1(1), 12–16.

Aziz S, Rahman MM, Islam MS. 2016. Fatty acid composition and phytochemical analysis of selected medicinal plant extracts. Journal of Scientific Research 8(2), 145–152.

Arulselvan P, Subramanian SP. 2007. Beneficial effects of Murraya koenigii leaves on antioxidant defense system and ultrastructural changes of pancreatic β-cells in experimental diabetes in rats. Chemico-Biological Interactions 165(2), 155–164. https://doi.org/10.1016/j.cbi.2006.10.014

Baliga MS, Jagetia GC, Rao SK, Babu K. 2003. Evaluation of nitric oxide scavenging activity of certain species in vitro: A preliminary study. Nahrung 47(4), 261–265. https://doi.org/10.1002/food.200390061

Banso A, Adeyemo SO. 2007. Evaluation of antibacterial properties of tannins isolated from Dichrostachys cinerea. African Journal of Biotechnology 6(15), 1785–1787. https://doi.org/10.5897/AJB2007.000-2262

Basit MA, Arifah AK, Chwen LT, Salleh A, Kaka U, Idris SB, Farooq AA, Javid MA, Murtaza S. 2023. Qualitative and quantitative phytochemical analysis, antioxidant activity and antimicrobial potential of selected herbs Piper betle and Persicaria odorata leaf extracts. Asian Journal of Agriculture and Biology 3. https://doi.org/10.35495/ajab.2023.038

Furuhashi M, Hotamisligil GS. 2008. Fatty acid-binding proteins: Role in metabolic diseases and potential as drug targets. Nature Reviews Drug Discovery 7(6), 489–503. https://doi.org/10.1038/nrd2589

Ghani A. 1998. Medicinal plants of Bangladesh: chemical constituents and uses (2nd ed.). Asiatic Society of Bangladesh.

Harborne JB. 1984. Phytochemical methods: A guide to modern techniques of plant analysis. Chapman and Hall, London.

He M, Qin CX, Wang X, Ding NZ. 2020. Plant unsaturated fatty acids: Biosynthesis and regulation. Frontiers in Plant Science 11, 390. https://doi.org/10.3389/fpls.2020.00390

Ivanova D, Gerova D, Chervenkov T, Yankova T. 2005. Phytochemical and antioxidant capacity of Bulgarian medicinal plants. Journal of Ethnopharmacology 96(1), 145–150.

Iyer UM, Mani UV. 1990. Studies on the effect of curry leaves supplementation (Murraya koenigii) on lipid profile, glycated proteins and amino acids in non-insulin dependent diabetic patients. Plant Foods for Human Nutrition 40, 275–279. https://doi.org/10.1007/BF02193851

Lunn JE, Feil R, Hendriks JH, Gibon Y, Morcuende R, Osuna D, Scheible WR, Carillo P, Hajirezaei MR, Stitt M. 2006. Sugar-induced increases in trehalose 6-phosphate are correlated with redox activation of ADP-glucose pyrophosphorylase and higher rates of starch synthesis in Arabidopsis thaliana. Biochemical Journal 397(1), 139–148. https://doi.org/10.1042/BJ20060083

Mandal V, Mohan Y, Hemalatha S. 2007. Microwave-assisted extraction: An innovative and promising extraction tool for medicinal plant research. Pharmacognosy Reviews 1(1), 7–18.

Misra A. 2009. Studies on biochemical and physiological aspects in relation to phytomedicinal qualities and efficacy of the active ingredients during handling, cultivation and harvesting of medicinal plants. Journal of Medicinal Plants Research 3(13), 1140–1146.

Muthumani P, Venkatraman S, Ramseshu KV, Meera R, Devi P, Kameswari B, Eswarapriya B. 2009. Pharmacological studies of anticancer and anti-inflammatory activities of Murraya koenigii Spreng in experimental animals. Journal of Pharmaceutical Sciences and Research 1(3), 137–141.

Pande MS, Gupta SPBN, Pathak A. 2009. Hepatoprotective activity of Murraya koenigii Linn bark. Journal of Herbal Medicine and Toxicology 3(1), 69–71.

Peichev M, Naiyer AJ, Pereira D, Zhu Z, Lane WJ, Williams M, Oz MC, Hicklin DJ, Witte L, Moore MA. 2000. Expression of VEGFR-2 and AC133 by circulating human CD34+ cells identifies a population of functional endothelial precursors. Blood 95(3), 952–958. https://doi.org/10.1182/blood.V95.3.952

Reifen R, Karlinsky A, Stark AH, Berkovich Z, Nyska A. 2015. α-Linolenic acid (ALA) is an anti-inflammatory agent in inflammatory bowel disease. Journal of Nutritional Biochemistry 26(12), 1632–1640. https://doi.org/10.1016/j.jnutbio.2015.08.006

Ristić-Medić D, Vučić V, Takić M, Karadžić I, Glibetić M. 2013. Polyunsaturated fatty acids in health and disease. Journal of the Serbian Chemical Society 78(9), 1269–1289. https://doi.org/10.2298/JSC130402040R

Shahin A, Sahal A, Sharmin AI, Tanzima P. 2016. Analysis of fatty acid and determination of total protein, alkaloid, saponin, flavonoid of Bangladesh Bombax ceiba Linn leaves and seeds. Indian Journal of Pharmaceutical and Biological Research 4(4), 33–38. https://doi.org/10.30750/ijpbr.4.4.7

Shahin A, Tahmina KM. 2019. Analysis of fatty acid and determination of total protein and phytochemical content of Cassia sophera Linn leaf, flower and seed. Beni-Suef University Journal of Basic and Applied Sciences 8, 1–9. https://doi.org/10.1186/s43088-019-0004-1

Shashank T, Talreja S. 2020. Pharmaceutical importance of Murraya koenigii: A complete study. Indian Journal of Public Health Research and Development 11.

Wendell SG, Baffi C, Holguin F. 2014. Fatty acids, inflammation, and asthma. Journal of Allergy and Clinical Immunology 133(5), 1255–1264.

Winterkorn H, Fang H. 1991. Analysis of fatty acid methyl esters by gas chromatography. Journal of the American Oil Chemists’ Society 68(5), 317–320.

Zielińska A, Nowak I. 2014. Fatty acids in plant oils and their importance in cosmetics. Chemik 68(2), 103–110.

Related Articles

The role of aberrant glycosylation in autoimmune disease development and progression

Md. Nafis Fuad Prottoy, Sayad Md. Didarul Alam*, Int. J. Biosci. 28(6), 1-12, June 2026.

Limonene-enhanced botanical fungicides: A sustainable component of integrated tomato powdery mildew management in the tropical region

Edmund F. Luena*, Angela G. Mkindi, Akida I. Meya, Nelson S. Mpumi, Steven R. Belmain, Int. J. Biosci. 28(5), 52-65, May 2026.

Kapwa (Shared identity): The case of being community health workers (CHWs) in Cagayan Province, Philippines

Jay Emmanuel L. Asuncion, Julius T. Capili, Jinky Marie T. Chua*, Pauline Grace P. Casil-Batang, Lara Melissa G. Luis, Dorina D. Sabatin, Krisha Anne A. Hipolito, Ethel Marie M. Mangada, Int. J. Biosci. 28(5), 43-51, May 2026.

Effects of corn silage-based diets on carcass and meat characteristics of Philippine native swamp buffalo (Bubalus bubalis carabanensis)

Vince Randolf R. Sumajit*, Phoebe Lyndia T. Llantada, Ann-Sherly R. Dugyon, Int. J. Biosci. 28(5), 36-42, May 2026.

Assessment of the knowledge, attitude, and practices of frontliners toward community-acquired pneumonia in the Cagayan, Philippines

Jinky Marie T. Chua*, Nikko Alexander S. Pacquing, Ann P. Chua, Ethel Marie M. Mangada, Int. J. Biosci. 28(5), 26-35, May 2026.

Therapeutic potential of protocatechuic acid in in silico evaluation, antioxidant activity, and anti-inflammatory effects for cardiovascular health

Bhavadharseny Uma Shanmugasundaram, Subashini Ragunathan*, Int. J. Biosci. 28(5), 1-10, May 2026.

African swine fever outbreak in Camiguin Island, Philippines: An analysis of biosecurity and control strategies

Nena V. Siaboc*, Libby Jay Roasol Cascon, Int. J. Biosci. 28(4), 199-208, April 2026.