Role of probiotics in health and diseases

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Research Paper 01/02/2019
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Role of probiotics in health and diseases

Dina M. Trabzuni
Int. J. Biosci.14( 2), 319-325, February 2019.
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Probiotics are found inside our body, in food as dairy product and in the form of supplements. It’s very beneficial for health, especially for digestive system. So, it become very obvious to increase the use of probiotics as a supplement for treating or preventing some diseases such as food allergy, autism, cholesterol and others. The purpose of this study is to review the current documentation for the claims of health benefits derived from the use of probiotics. Articles relating to modes of action and randomized control trials of treatment were reviewed by searching PubMed, google using terms ‘probiotic’, ” autism”, “lactic acid bactera” and so on. Intestinal micro biota plays an important role in the mechanism of allergic diseases through maintaining balance of the Type1T helper/ Type2T helper (Th1/Th2), transforming growth factor beta (TGF-β) expression and production of Foxp3+ regulatory T (Treg) cells. On other hand, there is a difference in gut microbiota for Autism Spectrum Disorders (ASD) children with a control group. Moreover, some strains and species of lactic acid bacteria (LAB) reduce serum and liver cholesterol and triglycerides with high-fat diet. This review supports the safety of probiotics but further studies are required to facilitate better treatment and hence improved efficacy.


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