Anticytotoxic and antioxidant activities of ethanolic extract of dried flowers of Moringa oleifera
Paper Details
Anticytotoxic and antioxidant activities of ethanolic extract of dried flowers of Moringa oleifera
Abstract
Moringa oleifera is a common plant and known for various medicinal properties. The research work was conducted to investigate the anticytotoxic and antioxidant activity of dried flower powder extract of leaf Moringa oleifera. The ethanol extracts from flower of moringa plants contain severalphytochemicals such asalkaloids,amino acids, quinones, cardiac glycosides, flavonoids, phenols, saponins, tannins, terpenoids, coumarins and triterpenoids.The antioxidant activities of different concentrations of ethanol extracts of the leaves were determined by the three assay techniques i.e., DPPH radical scavenging assay, Ferric reducing ability power (FRAP). The type of chemical bonds is identified through FTIR analysis. The results obtained in the present study indicate that the leaves of Moringa oleifera are a potential source of anticytotoxic and antioxidants.
Bharali R, Tabassum J, Azad MR. 2003. Chemo modulatory effect of Moringa oleifera Lam. on hepatic carcinogen metabolising enzymes, antioxidant parameters and skin papilloma genesis in mice. Asian Pac J Cancer Prev. 4(2), 131.
Brown J E and Rice Evans CA, 1998. Luteolin rich artichoke extract protects low density lipoprotein from oxidation in vitro. Free Radical Res. 29, 247-255.
Caceres A, Saraiva A, Rizzio S, Zabala L, De Leon E, Navy F, 1992. Pharmacological properties of Moringa oleifera. 2: screening for antispasmodic, anti-inflammatory and diuretic activity. J Ethnopharmacology 36(3), 233
Clarke Hans Thacher, 2007. A Handbook of Organic Analysis, IV Edn., CBS Publishers, New Delhi. Devi Pratibha.
Donli PO, Dauda H. 2003. Evaluation of aqueous Moringa seed extract as a seed treatment bio fungicide for groundnuts. Pest Management Sci. 59(9), 1060.
Eilert U, Wolters B, Narsdtedt A. 1981. The antibiotic principle of seeds of Moringa oleiferaand Moringa stenopetala. Planta Med. 42(1), 55.
Fahey J, 2005. Moringa oleifera: A review of the medical evidence for its nutritional, therapeutic, and prophylactic properties. Part 1. Trees for Life Journal 1(5), 231.
Özcan MM, Ghafoor K, Juhaimi F, Ahmed IAM, Babiker EE. 2019. Effect of cold-press and soxhlet extraction on fatty acids, tocopherols and sterol contents of the Moringa seed oils. South African Journal of Botany 124, 333-337.
Adams HR, CampBJ. 1996. The isolation and identification of three alkaloids from Acacia berlandieri. Toxicon 4(2), 85-90.
Jha DK, Panda L, Lavanya P, Ramaiah S, Anbarasu A. 2012. Detection and confirmation of alkaloids in leaves of Justicia adhatoda and bioinformatics approach to elicit its anti-tuberculosis activity. Applied biochemistry and Biotechnology 168, 980-990.
Verma KC, Verma SK. 2010. Alkaloids analysis in root and leaf fractions of Sarpagandha (Rauwolfia serpentina). Agricultural Science Digest 30(2), 133-135.
Yemm EW, Cocking EC, Ricketts RE. 1995. The determination of amino-acids with ninhydrin. Analyst 80(948), 209-214.
Bitenc J, Pavčnik T, Košir U, Pirnat K. 2020. Quinone based materials as renewable high energy density cathode materials for rechargeable magnesium batteries. Materials 13(3), 506.
Ebana RUB, Madunagu BE, Ekpe ED,Otung IN. 1991. Microbiological exploitation of cardiac glycosides and alkaloids from Garcinia kola, Borreriaocymoides, Kola nitida and Citrus aurantifolia. Journal of Applied Microbiology 71(5), 398-401.
Sankhalkar S, Vernekar V. 2016. Quantitative and Qualitative analysis of Phenolic and Flavonoid content in Moringa oleifera Lam and Ocimum tenuiflorum L. Pharmacognosy Research 8(1), 16.
Santhi K, Sengottuvel R. 2016. Qualitative and quantitative phytochemical analysis of Moringa concanensis Nimmo. International Journal of Current Microbiology and Applied Sciences, 5(1), 633-640.
Sharma V, Paliwal R. 2013. Isolation and characterization of saponins from Moringa oleifera (Moringaceae) pods. Int J. Pharm. Pharm. Sci, 5(1), 179-183.
Teixeira EMB, Carvalho MRB, Neves VA, Silva, MAArantes-Pereira L. 2014. Chemical characteristics and fractionation of proteins from Moringa oleifera Lam. Leaves. Food chemistry, 147, 51-54.
Santhi K, Sengottuvel R. 2016. Qualitative and quantitative phytochemical analysis of Moringa concanensis Nimmo. International Journal of Current Microbiology and Applied Sciences, 5(1), 633-640.
Kasolo JN, Bimenya GS, Ojok L, Ochieng J, Ogwal-Okeng JW. 2010. Phytochemicals and uses of Moringa oleifera leaves in Ugandan rural communities.
UC R, NAIR VMG. 2013. Phytochemical analysis of successive reextracts of the leaves of Moringa oleifera Lam. International Journal of Pharmacy and pharmaceutical sciences, 5, 629-634.
Singleton VL, Orthofer R, Lamuela-Raventós RM. 1999. Analysis of total phenols and other oxidation substrates and antioxidants by means of folin-ciocalteu reagent. In Methods in enzymology. 299, 152-178.
Marinova, Batchvarov V. 2011. Evaluation of the methods for determination of the free radical scavenging activity by DPPH. Bulgarian Journal of Agricultural Science, 17(1), 11-24.
Nobossé P, Fombang EN, Mbofung CM. 2018. Effects of age and extraction solvent on phytochemical content and antioxidant activity of fresh Moringa oleifera L. Leaves. Food science & nutrition 6(8), 2188-2198.
Steenkamp V, Gouws MC. 2006. Cytotoxicity of six South African medicinal plant extracts used in the treatment of cancer. South African Journal of Botany 72(4), 630-633.
Shaw JE, Sicree RA, Zimmet PZ. 2010. Global estimates of the prevalence of diabetes for2010 and 2030. Diabetes Res. Clin. Pract. 87, 4–14.
Barik R, Jain S, Qwatra D. 2008. Antidiabetic activity of aqueous root extract of Ichnocarpus frutescens in STZ-nicotinamide induced type II diabetes in rats. Indian J. Pharmacol. 40, 19.
Vincent AM, Russell JW, Low P. 2004. Oxidative stress in the pathogenesis of diabetic. 612-28.
Pari L, Latha M. 2005. Antidiabetic effect of Scopariadulcis: Effect on lipid peroxidation streptozotocin diabetes. Gen. Physiol. Biophys. 24, 13-26.
Heim KE, Tagliaferro AR, Bobilya DJ. 2002. Flavonoid antioxidants: chemistry, metabolism, and structure activity relationships. J Nutr. Biochem. 13, 572- 584.
Picton SF, Flatt PR, McClenghanNH. 2001. Differential acute and long-term actions of succinicacid monomethyl ester exposure on insulin secreting BRAIN-BD 11 cells. Int. J. Exp. Diab. Res. 2, 19- 27.
G. Rajeswari, S. Parvathi, S. Palanival (2024), Anticytotoxic and antioxidant activities of ethanolic extract of dried flowers of Moringa oleifera; JBES, V24, N3, March, P155-163
https://innspub.net/anticytotoxic-and-antioxidant-activities-of-ethanolic-extract-of-dried-flowers-of-moringa-oleifera/
Copyright © 2024
By Authors and International
Network for Natural Sciences
(INNSPUB) https://innspub.net
This article is published under the terms of the
Creative Commons Attribution License 4.0