Pulmonary candidiasis in immunocompromised patients seen at Befelatanana University Hospital from 2018 to 2019
Paper Details
Pulmonary candidiasis in immunocompromised patients seen at Befelatanana University Hospital from 2018 to 2019
Abstract
The Candidiasis occupies an increasingly important place in infectious pulmonary diseases in recent decades. The objectives of this study were to determine the incidence of yeast Candida spp in pulmonary samples, to describe the clinical and socio-demographic characteristics of these pulmonary infections and to propose suggestions to clinicians and biologists who analyze these pulmonary samples. This is a prospective and descriptive study from April 2018 to March 2019 in the laboratory of Joseph Raseta Befelatanana University Hospital. All Candida spp yeast positive pulmonary samples were identified by filamentation testing. The data was entered on the Epi-info 3.5.2 software. For a period of one year, 17 of the 107 pulmonary sampling (15.9%) were positive for yeasts of the genus Candida spp. Of these yeasts, 82.4% are represented by the species Candida albicans. The patients aged 40 and over (8.4%), the men (8.4%), the patients with pneumopathy (10.3%) and the patients hospitalized in the surgical resuscitation department (7.5%) were most affected by Candida albican. Simultaneous bacteriological examination showed a predominance of Acinetobacter bacteria. This study has highlighted the pertinence of mycological examination of any pulmonary sampling in the hospitalized and immunocompromised patients. The use of specific culture media for mycotic pathogens will increase the positivity of the mycological examination.
Adou-Bryn KD, Ouhon J, Assoumou A, Kassi EA, Kone M. 1999. Fungi and parasites isolated on examination of 142 bronchial aspiration fluids in Abidjan. Médecine d’Afrique Noire 46, 363-365.
Agban A, Gbogbo KA, Hoekou YP, Atchou K, Tchacondo T, et al. 2013. Evaluation of the antifungal activity of extracts of Cassia alata L. and Piliostigma thonningii (Schumach.) Milne Redh. (Fabaceae) on Candida albicans. International Journal of Biological and Chemical Sciences 7, 1041-1047.
Azoulay E, Limal N, Mayaud C, Schlemmer B. 2001. Candida positive lung sampling: nosocomial infection or colonization? Reanimation 10, 323-328.
Cateau E, Rodier MH, Imbert C. 2012. Could antifungal lock be useful in the management of candidiasis linked with catheters? Medecine Science 28, 740-745.
Chabasse D, Pihet M, Bouchara JP. 2009. Emergence of new pathogenic fungi in medicine. Revue Francophone des Laboratoires 416, 71-86.
Gauzit R. 2001. Epidemiology and risk factors of systemic candidiasis in intensive care. Annales françaises d’anesthésie et de réanimation 20, 394-399.
Jha BJ, Dey S, Tamang MD, Joshy ME, Shivananda PG. 2006. Characterization of Candida species isolated from cases of lower respiratory tract infection. Kathmandu University Medical Journal 4, 290-294.
Laurent M, Gogly B, Tahmasebi F, Paillaud E. 2011. Oropharyngeal candidiasis of elderly patients. Geriatrie et Psychologie Neuropsychiatrie du viellissement 9, 21-28.
Mjabber A , Moutaouakil A, El Aziz S, Chadli A, El Ghomari A, Farouqi A. 2010. P137 Candidiasis and diabetes. Diabetes & Metabolism 36, A71.
Vincent JL, Rello J, Marshall J, Silva E, Anzueto A. 2009. International study of the prevalence and outcomes of infection in intensive care units. Journal of the American Medical Association 302, 2323-2329.
Vincent JL, Safr Y, Sprung C, Ranieri VM, Reinhart K. 2006. Sepsis in European intensive care units: result of the SOAP study. Critical Care Medicine 34, 344-353.
Zarrinfar H, Kaboli S, Dolatabadi S, Mohammadi R. 2016. Rapid detection of Candida species in bronchoalveolar lavage fluid from patients with pulmonary symptoms. Brazilian Journal of Microbiology 47, 172-176.
Zafindrasoa Domoina Rakotovao-Ravahatra, Nambininiavo Marianne Ranorohasimanana, Fenosoa Anita Tsatoromila, Zakasoa Mbololona Ravaoarisaina, Fidiniaina Mamy Randriatsarafara, Andriamiadana Luc Rakotovao, Lala Rasoamialy-Soa Razanakolona, 2019. Pulmonary candidiasis in immunocompromised patients seen at Befelatanana University Hospital from 2018 to 2019. Int. J. Microbiol. Mycol., 10(2), 1-6.
Copyright © 2019 by the Authors. This article is an open access article and distributed under the terms and conditions of the Creative Commons Attribution 4.0 (CC BY 4.0) license.