Purification and analysis of secondary metabolites from actinomycetes isolated from red soil: Insights into their therapeutic application
Paper Details
Purification and analysis of secondary metabolites from actinomycetes isolated from red soil: Insights into their therapeutic application
Abstract
Actinomycetes, isolated from soil can produce diverse secondary metabolites with valuable therapeutic applications. This study aimed to isolate actinomycetes from red soil and evaluate their antibacterial, antioxidant, and biofilm-forming potential. Selected isolates exhibited significant antibacterial activity against Gram-positive bacteria in agar well diffusion assays. Further chemical characterization of their secondary metabolites using spectroscopic techniques confirmed the presence of functional groups responsible for their bioactivity. Antioxidant activity was assessed using free radical scavenging assays, revealing strong antioxidant capacity. Additionally, the isolates demonstrated notable biofilm-forming ability, essential for their survival in harsh environments, and may contribute to antibiotic resistance. These soil-derived actinomycetes’ combined antibacterial and antioxidant properties highlight their potential as sources of natural compounds for pharmaceutical applications. The findings support the need for further studies on these bioactive compounds’ toxicity, formulation, and clinical relevance. This research contributes to the growing interest in natural product discovery and provides promising candidates for developing alternative antimicrobial and antioxidant agents from red soil actinomycetes.
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A. Amrin, M. Muthuselvam, Radha Palaniswamy (2025), Purification and analysis of secondary metabolites from actinomycetes isolated from red soil: Insights into their therapeutic application; IJMM, V20, N5, May, P15-25
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